Molecular species | 4 months | 10 months | 15 months | |||
---|---|---|---|---|---|---|
Fold Changes1 | p-value2 | Fold Changes1 | p-value2 | Fold Changes1 | p-value2 | |
Phosphatidylcholine (PC) | ||||||
16:1LPC | 0.99 | 0.960 | 0.59 | 0.026* | 1.07 | 0.724 |
18:0LPC | 1.50 | 0.019* | 1.27 | 0.281 | 1.01 | 0.921 |
20:5LPC 3 | 1.45 | 0.011* | 0.82 | 0.440 | 1.26 | 0.190 |
22:6LPC | 1.45 | 0.011* | 1.03 | 0.889 | 1.10 | 0.619 |
34:1PC (16:0/18:1) | 1.24 | 0.037* | 1.00 | 0.983 | 1.27 | 0.071 |
34:2PC (16:0/18:2) | 1.27 | 0.053 | 1.17 | 0.007** | 1.21 | 0.015* |
34:3PC (16:0/18:3) | 1.06 | 0.698 | 0.65 | 0.034* | 0.98 | 0.936 |
35:2PC | 1.68 | 0.030* | 1.55 | 0.013* | 1.27 | 0.035* |
36:1PC (18:0/18:1) | 1.55 | 0.010** | 1.16 | 0.256 | 1.19 | 0.109 |
36:2PC (18:0/18:2) | 1.48 | 0.024* | 1.35 | 0.017* | 1.11 | 0.139 |
36:5PC (16:0/20:5) | 1.51 | 0.011* | 0.81 | 0.509 | 1.40 | 0.374 |
37:2PC (19:0/18:2) | 1.33 | 0.144 | 1.47 | 0.008** | 1.26 | 0.071 |
38:3PC (18:0/20:3) | 1.52 | 0.045* | 1.38 | 0.209 | 1.17 | 0.497 |
38:4PC (18:1/20:3) | 0.99 | 0.957 | 0.63 | 0.031* | 0.82 | 0.137 |
38:5PC (18:0/20:5) | 1.74 | 0.008** | 1.08 | 0.783 | 1.24 | 0.266 |
38:5PC (18:1/20:4) | 1.13 | 0.331 | 0.79 | 0.018* | 0.84 | 0.149 |
38:7PC | 1.08 | 0.644 | 0.48 | 0.019* | 0.94 | 0.807 |
40:4PC (20:0/20:4) | 1.50 | 0.018* | 1.47 | 0.077 | 1.12 | 0.313 |
40:5PC (18:0/22:5) | 1.71 | 0.007** | 1.25 | 0.182 | 1.30 | 0.349 |
40:6PC (18:0/22:6) | 1.64 | 0.033* | 1.39 | 0.099 | 1.06 | 0.629 |
40:7PC (18:1/22:6) | 1.06 | 0.642 | 0.72 | 0.022* | 0.73 | 0.072 |
42:6PC (20:0/22:6) | 1.41 | 0.002** | 1.52 | 0.012* | 1.38 | 0.110 |
34:2ePC (16:0e/18:2) | 1.52 | <0.001*** | 1.81 | <0.001*** | 1.47 | 0.011* |
phosphatidylinositol (PI) | ||||||
38:5PI (18:0/20:5) | 1.53 | 0.024* | 0.92 | 0.748 | 2.00 | 0.002** |
Sphingomyelin (SM) | ||||||
34:1SM (d18:1/N16:0) | 1.25 | 0.057 | 1.35 | 0.027* | 1.30 | 0.032* |
42:2SM | 1.37 | 0.051 | 1.39 | 0.024* | 1.38 | 0.069 |
42:3SM (d18:2/N24:1) | 1.48 | 0.030* | 1.22 | 0.061 | 1.30 | 0.141 |
Triacylglycerol (TAG) | ||||||
52:3TAG (16:0/18:1/18:2) | 1.21 | 0.557 | 1.21 | 0.558 | 0.58 | 0.045* |
52:4TAG (16:0/18:2/18:2) | 1.57 | 0.250 | 1.41 | 0.421 | 0.40 | 0.032* |
52:5TAG (16:0/18:2/18:3) | 1.04 | 0.903 | 0.74 | 0.314 | 0.49 | 0.011* |
54:3TAG (18:0/18:1/18:2) | 0.64 | 0.553 | 0.62 | 0.411 | 0.48 | 0.043* |
54:4TAG (18:1/18:1/18:2) | 0.93 | 0.919 | 0.97 | 0.950 | 0.37 | 0.038* |
56:6TAG (18:0/18:2/20:4) | 2.00 | 0.209 | 2.75 | 0.016* | 0.82 | 0.500 |
58:10TAG (16:0/20:4/22:6) | 1.40 | 0.311 | 2.07 | 0.020* | 0.88 | 0.509 |
58:11TAG | 2.44 | 0.038* | 1.92 | 0.027* | 1.70 | 0.205 |
58:11TAG | 1.87 | 0.030* | 1.69 | 0.176 | 1.64 | 0.383 |
58:12TAG (18:3/20:4/20:5) | 2.06 | 0.032* | 1.91 | 0.168 | 2.65 | 0.005** |
60:10TAG | 1.68 | 0.131 | 2.24 | 0.021* | 0.90 | 0.762 |
60:11TAG (16:2/22:4/22:5) | 1.43 | 0.178 | 2.04 | <0.001*** | 1.51 | 0.168 |
60:11TAG (16:0/22:5/22:6) | 1.66 | 0.335 | 1.98 | 0.007** | 1.39 | 0.401 |
60:11TAG (18:2/20:3/22:6) | 1.80 | 0.018* | 2.13 | 0.005** | 1.42 | 0.304 |
60:12TAG (18:2/20:5/22:5) | 1.67 | 0.106 | 1.75 | 0.177 | 2.80 | 0.011* |
60:12TAG (18:3/20:4/22:5) | 1.38 | 0.375 | 2.85 | 0.007** | 1.37 | 0.356 |
60:12TAG (18:3/20:4/22:5) | 2.25 | 0.039* | 2.08 | 0.068 | 2.81 | 0.087 |
60:12TAG (18:3/20:4/22:5) | 2.29 | 0.154 | 2.04 | 0.021* | 1.64 | 0.308 |
60:13TAG (18:2/20:5/22:6) | 1.66 | 0.086 | 2.00 | 0.015* | 2.58 | 0.067 |
62:11TAG (18:2/22:4/22:5, 16:1/22:5/24:5) | 1.64 | 0.063 | 1.77 | 0.031* | 1.58 | 0.232 |
62:12TAG (18:3/22:4/22:5) | 1.56 | 0.147 | 2.27 | 0.003** | 1.35 | 0.370 |
62:13TAG (16:1/22:6/24:6, 20:2/20:5/22:6) | 2.28 | 0.121 | 1.77 | 0.003** | 1.82 | 0.363 |
62:13TAG (18:1/22:6/22:6) | 2.09 | 0.106 | 2.36 | 0.029* | 2.53 | 0.272 |
62:14TAG (18:2/22:6/22:6) | 2.25 | 0.119 | 2.45 | <0.001*** | 2.20 | 0.274 |
64:14TAG | 1.57 | 0.215 | 2.06 | 0.008** | 1.95 | 0.251 |
65:14TAG | 1.83 | 0.052 | 2.03 | <0.001*** | 1.52 | 0.299 |
Cholesterol ester (ChE) | ||||||
18:1ChE | 0.74 | 0.016* | 0.78 | 0.089 | 1.12 | 0.423 |
18:2ChE | 1.16 | 0.170 | 1.17 | 0.029* | 1.16 | 0.307 |
20:5ChE | 1.38 | 0.041* | 0.93 | 0.762 | 1.33 | 0.138 |