Skip to main content

Table 1 Calculated LP/SOD ratio and ROS generated in response to supplementation of 180 μM of various PUFAs and 10 μM of methotrexate for 48 hours by various cells

From: Effects of polyunsaturated fatty acids on the growth of gastric cancer cells in vitro

Treat-ment

LP/SOD ratio in GES1

% of viable GES1 cells at 180 μM

LP/SOD ratio in MGC

% of viable MGC cells at 180 μM

LP/SOD ratio in SGC

% of viable SGC cells at 180 μM

LXA4in the medium expressed in pg/ml GES1

LXA4in the medium in pg/ml MGC

LXA4in the medium in pg/ml SGC

ROS generated

 

GES% of C

MGC% of C

SGC% of C

C

1.0

100

1.0

100

1.0

100

90

170

130

100

80

85

LA

5.0

4

7.4

70

3.9

20

125

125

100

175

325

140

ALA

50.0

20

27.3

90

13.1

60

135

120

150

150

150

150

AA

5.7

60

3.7

40

68.5

40

80

280

110

25

65

120

EPA

10.0

40

9.7

80

108.4

80

170

175

70

250

60

150

DHA

15.7

90

42.0

85

20.0

85

110

160

75

25

425

155

Metho-

trexate 10 μM

1.0

60

0.63

30

0.91

30

120

110

100

150

160

70

  1. C = Control.