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Table 1 Calculated LP/SOD ratio and ROS generated in response to supplementation of 180 μM of various PUFAs and 10 μM of methotrexate for 48 hours by various cells

From: Effects of polyunsaturated fatty acids on the growth of gastric cancer cells in vitro

Treat-ment LP/SOD ratio in GES1 % of viable GES1 cells at 180 μM LP/SOD ratio in MGC % of viable MGC cells at 180 μM LP/SOD ratio in SGC % of viable SGC cells at 180 μM LXA4in the medium expressed in pg/ml GES1 LXA4in the medium in pg/ml MGC LXA4in the medium in pg/ml SGC ROS generated
  GES% of C MGC% of C SGC% of C
C 1.0 100 1.0 100 1.0 100 90 170 130 100 80 85
LA 5.0 4 7.4 70 3.9 20 125 125 100 175 325 140
ALA 50.0 20 27.3 90 13.1 60 135 120 150 150 150 150
AA 5.7 60 3.7 40 68.5 40 80 280 110 25 65 120
EPA 10.0 40 9.7 80 108.4 80 170 175 70 250 60 150
DHA 15.7 90 42.0 85 20.0 85 110 160 75 25 425 155
Metho-
trexate 10 μM
1.0 60 0.63 30 0.91 30 120 110 100 150 160 70
  1. C = Control.