Table 1 Characteristics of subjects included
From: Polymorphisms of PTPN11 gene could influence serum lipid levels in a sex-specific pattern
|  | All (n = 1003) | Male (n = 584) | Female (n = 419) | P |
|---|---|---|---|---|
Age (year) | 49 (45–55) | 49 (45–54) | 48 (44–56) | 0.640 |
Waist (cm) | 85 (77–92) | 90 (84–94) | 77 (72–83) | <0.001 |
BMI (Kg/m2) | 24.0 (21.9–26.2) | 24.9 (23.0–26.7) | 22.6 (20.7–24.9) | <0.001 |
TG (mmol/L) | 1.44 (0.98–2.12) | 1.61 (1.16–2.44) | 1.21 (0.84–1.73) | <0.001 |
TC (mmol/L) | 5.04 (4.49–5.66) | 5.03 (4.48–5.68) | 5.09 (4.52–5.64) | 0.669 |
HDL-C (mmol/L) | 1.33 (1.15–1.56) | 1.27 (1.10–1.45) | 1.48 (1.27–1.70) | <0.001 |
LDL –C (mmol/L) | 3.09 (2.63–3.60) | 3.10 (2.69–3.63) | 3.00 (2.53–3.54) | <0.001 |
rs2301756 | ||||
 GG | 750 (74.8%) | 439 (75.2%) | 311 (74.2%) | 0.625 |
 GA | 232 (23.1%) | 131 (22.4%) | 101 (24.1%) | |
 AA | 21 (2.1%) | 14 (2.4%) | 7 (1.7%) | |
rs12423190 | ||||
 TT | 515 (51.3%) | 304 (52.0%) | 211 (50.4%) | 0.782 |
 TC | 399 (39.8%) | 227 (38.9%) | 172 (41.0%) | |
 CC | 89 (8.9%) | 53 (9.1%) | 36 (8.6%) | |
rs12229892 | ||||
 GG | 342 (34.1%) | 189 (32.4%) | 153 (36.5%) | 0.271 |
 GA | 485 (48.4%) | 285 (48.8%) | 200 (47.7%) | |
 AA | 176 (17.5%) | 110 (18.8%) | 66 (15.8%) | |
rs7958372 | ||||
 TT | 751 (74.9%) | 439 (75.2%) | 312 (74.5%) | 0.962 |
 TC | 235 (23.4%) | 135 (23.1%) | 100 (23.9%) | |
 CC | 17 (1.7%) | 10 (1.7%) | 7 (1.7%) | |
rs4767860 | ||||
 AA | 335 (33.4%) | 198 (33.9%) | 137 (32.7%) | 0.666 |
 GA | 480 (47.9%) | 282 (48.3%) | 198 (47.3%) | |
 GG | 188 (18.7%) | 104 (17.8%) | 84 (20.0%) | |