Figure 3From: Oxidized eicosapentaenoic acids more potently reduce LXRα-induced cellular triacylglycerol via suppression of SREBP-1c, PGC-1β and GPA than its intact formEffects of EPA and OEPA on TG synthesis in HepG2 cells. Each fatty acid (60 μM) was added to HepG2 cells with T0901317 (10 nM) and vitamin E (10 μM) as noted in serum-free medium containing 0.1% BSA for 48 h. The final ethanol concentration was 0.3%. The increased TG level per mg protein (TG level after 48 h of incubation minus the level of reference cells) is shown. Data are reported as means ± SD (n = 3-4/group). Values with different letters are significantly different (p < 0.05).Back to article page