Table 1 Baseline characteristics of myocardial infarction cases and referents

Age at inclusion, years

53.4 ± 7.7

387

53.6 ± 7.7^a

752

53.4 ± 7.7

58.2 ± 7.5

158

58.3 ± 7.5^a

302

58.1 ± 7.5

Lag time to MI, years

n.a.

387

4.3 ± 2.5

n.a.

n.a.

n.a.

158

3.4 ± 2.4

n.a.

n.a.

BMI, kg/m²

26.3 ± 3.6

375

27.1 ± 3.7^b

727

25.9 ± 3.4

26.3 ± 4.7

86

26.7 ± 4.7

170

26.1 ± 4.8

Diabetes^c

7.2

361

11.1^d

695

5.2

7.7

78

9.0

156

7.1

Hypertension^c

50.5

373

62.2^b

721

44.4

57.4

84

72.6^d

165

49.7

Current smoking^c

24.9

365

38.4^b

723

18.1

28.3

152

46.7^b

297

18.9

Alcohol intake, g/day

5.5 ± 5.1

170

4.6 ± 4.6^d

367

5.9 ± 5.3

2.41 ± 2.70

35

2.4 ± 2.4

78

2.4 ± 2.8

Apo A1, g/L

1.40 ± 0.21

381

1.35 ± 0.21^b

734

1.42 ± 0.21

1.57 ± 0.26

155

1.51 ± 0.23^b

295

1.60 ± 0.27

Apo B, g/L

1.21 ± 0.27

381

1.29 ± 0.28^b

734

1.17 ± 0.26

1.22 ± 0.29

155

1.29 ± 0.26^b

295

1.18 ± 0.30

Apo B/ Apo A1 ratio

0.89 ± 0.25

381

0.98 ± 0.26^b

734

0.84 ± 0.23

0.80 ± 0.23

155

0.87 ± 0.2^b

295

0.75 ± 0.22

Homocysteine, μmol/L

11.41 ± 4.60

370

11.87 ± 3.83^e

700

11.16 ± 4.94

10.74 ± 4.36

155

12.19 ± 6.21^b

293

9.98 ± 2.67

Folate, nmol/L

9.69 ± 4.82

369

8.83 ± 4.45^b

700

10.14 ± 4.94

11.77 ± 10.14

155

10.64 ± 7.70

293

12.37 ± 11.19

B12, pmol/L

331 ± 158

370

329 ± 148

700

332 ± 162

359 ± 207

155

359 ± 260

293

359 ± 173

MTHFR 677C>T

n.a.

366

n.a.

693

n.a.

n.a.

148

n.a.

278

n.a.

CC

50.8

185

50.5

353

50.9

50.7

80

54.1

136

48.9

CT

40.6

150

41.0

280

40.4

39.2

55

37.2

112

40.3

TT

8.6

31

8.5

60

8.7

10.1

13

8.8

30

10.8

MTHFR 1298A>C

n.a.

367

n.a.

692

n.a.

n.a.

150

n.a.

278

n.a.

AA

39.0

136

37.1

277

40.0

43.9

62

41.3

126

45.3

AC

48.3

189

51.5

323

46.7

42.8

66

44.0

117

42.1

CC

12.7

42

11.4

92

13.3

13.3

22

14.7

35

12.6