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Table 1 Comparison between whole blood and cerebrospinal fluid fatty acids levels

From: Relationship between central and peripheral fatty acids in humans

Fatty acid

Whole blooda(%)

CSFa(%)

C:Dn-x

Common name

Mean (±SE)

Min

Max

Mean (±SE)

Min

Max

C16:0

palmitic acid

23.37 (0.43)

18.77

27.68

27.88 (0.76)

14.77

55.55

C16:1n-7

palmitoleic acid

2.56 (0.15)

0.75

4.43

2.71 (0.18)

0.89

7.24

C18:0

stearic acid

8.68 (0.28)

6.59

11.55

18.70 (0.78)

9.79

41.11

C18:1n-7

vaccenic acid

2.22 (0.08)

1.48

3.31

3.76 (0.17)

0.00

7.61

C18:1n-9

oleic acidc

21.21 (0.50)

15.8

26.17

25.48 (0.61)

11.74

33.94

C18:2n-6

linoleic acid

20.40 (0.53)

13.33

26.04

7.01 (0.33)

2.87

17.47

C18:3n-3

alpha-linolenic acid

0.74 (0.04)

0.46

1.42

2.54 (0.26)

0.59

16.14

C18:3n-6

gamma-linolenic acid

1.52 (0.06)

0.98

2.06

ND

-

-

C20:0

arachidic acid

0.26 (0.02)

0.12

0.51

ND

-

-

C20:1n-9

eicosenoic acid

0.24 (0.01)

0.17

0.37

1.21 (0.14)

0.00

6.14

C20:2n-6

eicosadienoic acid

1.17 (0.08)

0.30

2.01

ND

-

-

C20:3n-6

dihomo-gamma-linolenic acid

1.73 (0.05)

1.07

2.31

1.02 (0.12)

0.00

4.84

C20:4n-6

arachidonic acidb

8.00 (0.38)

4.78

12.47

3.47 (0.20)

0.99

9.00

C20:5n-3

eicosapentaenoic acid

2.01 (0.15)

1.04

3.87

1.87 (0.28)

0.00

10.66

C22:5n-3

docosapentaenoic acidc

1.98 (0.10)

1.06

3.17

2.94 (0.18)

0.84

8.46

C22:6n-3

docosahexaenoic acidc

3.91 (0.17)

2.54

5.92

1.41 (0.12)

0.00

5.70

Total SFA

32.31 (0.28)

29.06

35.20

46.58 (1.27)

24.57

75.94

Total MUFAb

26.26 (0.57)

18.92

31.71

33.16 (0.69)

14.55

41.21

Total omega-3 PUFAc

8.64 (0.33)

6.05

12.66

8.76 (0.55)

2.65

28.52

Total omega-6 PUFA

32.80 (0.53)

25.63

38.79

11.50 (0.49)

4.85

23.53

 

Ratio omega-6:omega-3

3.92 (0.13)

2.73

5.54

1.47 (0.07)

0.41

3.45

  1. Fatty acids are expressed as a percentage of total fatty acids.
  2. an = 28, bP < 0.05 for comparison between respective whole blood and CSF fatty acid concentrations using multiple linear regression.
  3. cP < 0.05 for comparison between whole blood total omega-3 PUFA and CSF DPA (C22:5n-3) and DHA (C22:6n-3) using multiple linear regression.
  4. ND not detected.