Prevalence of dyslipidemia with respect to TC, HDL, LDL, and TG in patients with DED and normal control subjects stratified by age in male (A) and female (B). There were statistically significant differences the prevalence of high cholesterol and low-density lipoprotein levels between female DED patients aged >65 years and those without DED. The differences in high cholesterol prevalence seen in patients aged 20–65 years were also statistically significant. TC, total cholesterol; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TG, triglycerides; DED, dry eye disease. *Statistically significant difference between the 2 groups. The cut-off value for dyslipidemia was any of the following: hypercholesterolemia (TC ≥ 200 mg/dL), hypertriglyceridemia (TG ≥150 mg/dL), low levels of HDL (<40 mg/dL), or high levels of LDL (≥100 mg/dL).