Figure 6From: Activation of the mitochondrial ATP-sensitive K+ channel reduces apoptosis of spleen mononuclear cells induced by hyperlipidemiaBlood serum from HTG mice induces superoxide generation in spleen mononuclear cells. Representative plots from flow cytometry analyses are shown in A, and means ± SEM are depicted in B. Cells (106 cells.ml-1) were incubated for 4 h in RPMI 1640 medium containing 10% serum obtained from WT (WT Serum) or HTG (HTG Serum) mice. Green line: WT cells in WT serum; blue line: HTG cells in WT serum; red line: WT cells in HTG serum; and yellow line: HTG cells in HTG serum. *P < 0.05 for 5HD vs. respective control condition. The results are expressed as means ± SEM, n = 9. #P < 0.05 vs. control WT cells in WT serum.Back to article page