Figure 3

Acsl5 KO mice display a normal dietary LCFA absorption from the intestine. Acsl5 WT and KO mice, females or males, (5 per group), were fasted overnight and than intravenously injected with tyloxapol to inhibit vascular lipases. Thirty minutes later the mice received a gastric bolus olive oil supplemented with radiolabeled oleic acid and retroorbital sinus blood samples were collected at 30, 60 and 90 min post gavage. Plasma radioactivity was determined by scintillation counting.