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Table 3 Concentration (ng/ml) of lipid mediators and precursors in human milk over time of lactation

From: High levels of anti-inflammatory and pro-resolving lipid mediators lipoxins and resolvins and declining docosahexaenoic acid levels in human milk during the first month of lactation

Compound

Time of lactation (days after birth)

R2

P

1-5

6-10

11-15

16-20

21-25

26-30

N=11-14

N=20-23

N=20-21

N=13-14

N=6

N=6-7

M

M

M

M

M

M

 

SD

SD

SD

SD

SD

SD

  

LTB4

9.48

10.01

10.19

8.47

9.31

7.78

0.51

0.44

8.59

4.43

5.28

6.31

5.64

3.34

LXA4

15.55

25.02

22.11

16.65

19.53

22.04

0.02

0.19

16.87

14.68

13.11

14.06

10.11

12.60

RvE1

4.24

5.23

8.15

4.60

12.57

5.67

0.19

0.13

5.76

3.91

11.45

4.08

15.20

5.65

RvD1

9.42

12.46

12.37

6.48

9.53

9.99

0.08

0.58

11.68

7.34

9.28

6.24

4.64

5.06

17-HDHA

53.38

40.73

34.04

22.72

14.76

28.27

0.71

0.0035

37.80

25.41

22.61

20.94

6.61

25.50

18-HEPE

7.20

7.29

8.99

6.28

9.80

8.30

0.18

0.063

5.02

2.63

3.92

4.54

6.60

3.29

15-HETE

28.38

24.19

26.90

25.35

22.80

26.04

0.22

0.60

16.44

12.86

11.72

17.85

8.33

19.65

12-HETE

43.90

38.46

36.71

28.12

28.75

23.63

0.95

0.39

 

26.61

29.11

15.99

19.37

15.80

11.55

  
  1. M, mean; SD, standard deviation; R2, coefficient of determination of linear trendline; P, p-value for linear trend (ANOVA)