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Table 8 Association of Tanis SNPs with HDL-C in Han and Uygur population

From: Genetic variation in Tanis was associated with elevating plasma triglyceride level in Chinese nondiabetic subjects

  

Mean HDL-C level

Model 1‡

Model 2§

 

Wild/Rare allele

Homozygous for rare allele

Heterozygous

Homozygous for wild allele

P Rec*

P Dom†

P Add

P Rec*

P Dom†

P Add

Han

          

rs12910524

C/T

1.28 ± 0.41

1.32 ± 0.44

1.30 ± 0.46

0.428

0.607

0.518

0.505

0.388

0.414

rs1384565

T/C

1.32 ± 0.54

1.31 ± 0.45

1.30 ± 0.42

0.499

0.772

0.792

0.516

0.682

0.787

rs2101171

T/C

1.27 ± 0.52

1.31 ± 0.44

1.31 ± 0.44

0.996

0.673

0.910

0.974

0.470

0.752

rs4965814

T/C

1.27 ± 0.47

1.31 ± 0.44

1.32 ± 0.43

0.442

0.215

0.430

0.289

0.186

0.335

Uygur

          

rs12910524

C/T

1.19 ± 0.42

1.24 ± 0.40

1.33 ± 0.54

0.127

0.025

0.059

0.285

0.065

0.062

rs1384565

T/C

1.64 ± 1.72

1.31 ± 0.34

1.25 ± 0.40

0.073

0.007

0.014

0.103

0.002

0.007

rs2101171

T/C

1.28 ± 0.50

1.22 ± 0.35

1.51 ± 0.51

0.096

0.498

0.131

0.341

0.347

0.126

rs4965814

T/C

1.39 ± 0.77

1.25 ± 0.38

1.25 ± 0.39

0.413

0.025

0.082

0.424

0.047

0.193

  1. §Analysis of covariance adjusted for sex, age, smoking, alcohol drinking, and GLU; ‡Unadjusted model; *recessive model; †dominant model; additive model.