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Figure 1 | Lipids in Health and Disease

Figure 1

From: Autophagy involved in lipopolysaccharide-induced foam cell formation is mediated by adipose differentiation-related protein

Figure 1

LPS enhances lipid accumulation during the macrophage foam cell formation. (A) Human THP-1 macrophages. (B-D) THP-1 macrophages were pre-treated with oxLDL (50 μg/ml) for 24 h and exposed to LPS (1 μg/ml) in RPMI1640 with 10% FBS for different periods (8, 16, and 24 h). Lipid droplets were visualized by Oil Red O staining. (E, F) The levels of triglcyceride (TG) and total cholesterol (TC) were evaluated. Data were presented as means ± S.E. of μM of triglyceride or cholesterol per milligram protein from 3 independent experiments. *significant difference from LPS treatment P < 0.05; **, P < 0.01.

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