Table 2 Distribution of MTHFR C677T genotype and allele in LG and non-LG
From: Enrichment of MTHFR 677 T in a Chinese long-lived cohort and its association with lipid modulation
Genotype n (%) | Allele n (%) | |||||
|---|---|---|---|---|---|---|
Group | N | CC | CT | TT | C | T |
All | 1009 | 700 (69.38) | 266 (26.36) | 43 (4.26) | 1666 (82.56) | 352 (17.44) |
LG | 516 | 332 (64.34) | 159 (30.81) | 26 (4.84) | 823 (79.75) | 209 (20.25) |
non-LG | 493 | 368 (74.65) | 107 (21.70) | 18 (3.65) | 843 (85.50) | 143 (14.50) |
χ2 | - | 12.639 | 11.573 | |||
P | - | 0.002 | 0.001 | |||
LG | ||||||
Male | 127 | 83 (65.35) | 35 (27.56) | 9 (7.09) | 201 (79.13) | 53 (20.87) |
Female | 389 | 249 (64.01) | 124 (31.88) | 16 (4.11) | 622 (79.95) | 156 (20.05) |
χ2 | - | 2.353 | 0.079 | |||
P | - | 0.308 | 0.779 | |||
non-LG | ||||||
Male | 142 | 95 (66.90) | 38 (26.76) | 9 (6.32) | 228 (80.28) | 56 (19.72) |
Female | 351 | 273 (77.78) | 69 (19.66) | 9 (2.56) | 615 (87.61) | 87 (12.39) |
χ2 | - | 7.896 | 8.750 | |||
P | - | 0.019 | 0.003 | |||
Male | ||||||
LG | 127 | 83 (65.35) | 35 (27.56) | 9 (7.09) | 201 (79.13) | 53 (20.87) |
non-LG | 142 | 95 (66.90) | 38 (26.76) | 9 (6.34) | 228 (80.28) | 56 (19.72) |
χ2 | - | 0.096 | 0.109 | |||
P | - | 0.953 | 0.741 | |||
Female | ||||||
LG | 389 | 249 (64.01) | 124 (31.88) | 16 (4.11) | 622 (79.95) | 156 (20.05) |
non-LG | 351 | 273 (77.78) | 69 (19.66) | 9 (2.56) | 615 (87.61) | 87 (12.39) |
χ2 | - | 16.830 | 15.771 | |||
P | - | 2.22E-4 | 7.15E-5 | |||