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Table 1 Association of CIMT or Framingham score with lipoprotein subfractions: generalized estimating equations multivariable analyses

From: Atherogenic subfractions of lipoproteins in the treatment of metabolic syndrome by physical activity and diet – the RESOLVE trial

Models with ApoA1 and ApoB

 

Outcome: CIMT

Outcome: Framingham score

Variables

Coefficient (95% CI)

P-value

Coefficient (95% CI)

P-value

Age, continuous

0.00 (-0.00 – 0.00)

0.173

0.11 (0.07 – 0.16)

<0.001

Body Mass Index, continuous

0.00 (-0.00 – 0.00)

0.441

0.05 (-0.00 – 0.11)

0.057

Diabetes Mellitus, yes

0.05 (0.02 – 0.08)

0.001

3.03 (2.52 – 3.54)

<0.001

ApoA1, continuous

-0.00 (-0.05 – 0.04)

0.959

-3.25 (-4.13 – -2.37)

<0.001

ApoB, continuous

0.01 (-0.04 – 0.05)

0.754

6.139 (5.32 – 6.96)

<0.001

Visit

-0.01 (-0.02 – -0.00)

0.019

-0.07 (-0.20 – 0.06)

0.288

Models with individual lipoprotein subfractions (without ApoA1 or ApoB)

Age, continuous

0.00 (-0.00 – 0.00)

0.170

0.10 (0.06 – 0.15)

<0.001

Body Mass Index, continuous

0.00 (0.01 – 0.00)

0.569

0.01 (-0.04 – 0.06)

0.718

Diabetes Mellitus, yes

0.05 (0.02 – 0.08)

0.002

2.94 (2.45 – 3.43)

<0.001

VLDL

-0.00 (-0.00 – 0.00)

0.942

0.01 (-0.02 – 0.32)

0.675

IDL-C

-0.00 (-0.00 – 0.00)

0.163

0.03 (-0.01 – 0.07)

0.189

IDL-B

0.00 (-0.00 – 0.00)

0.193

0.02 (-0.03 – 0.07)

0.426

IDL-A

-0.00 (-0.00 – 0.00)

0.827

0.05 (0.02 – 0.08)

0.002

Large LDL (1-2)

0.00 (-0.00 – 0.00)

0.442

0.036 (0.02 – 0.05)

<0.001

Small dense LDL (3-7)

0.00 (-0.00 – 0.00)

0.962

-0.01 (-0.06 – 0.04)

0.764

Large HDL

0.00 (-0.00 – 0.00)

0.631

-0.10 (-0.16 – -0.05)

<0.001

Intermediate HDL

-0.00 (-0.01 – 0.00)

0.187

-0.13 (-0.19 – -0.07)

<0.001

Small HDL

0.00 (-0.00 – 0.01)

0.497

-0.03 (-0.10 – 0.05)

0.484

Visit

-0.01 (-0.02 – -0.00)

0.015

-0.08 (-0.21 – 0.05)

0.245

  1. All models also controlled for sex, compliance, and exercise intensity type.
  2. Significant data (p<.05) are highlighted in bold.