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Table 4 Statistical information on group differences for AUC G and AUC I for salivary cortisol, serum cortisol and ACTH levels in response to acute stress

From: A soy-based phosphatidylserine/ phosphatidic acid complex (PAS) normalizes the stress reactivity of hypothalamus-pituitary-adrenal-axis in chronically stressed male subjects: a randomized, placebo-controlled study

  low stressed subjects high stressed subjects
salivary cortisol a       
  χ2 df p χ2 df p
AUCG 1.32 2 0.518 0.82 2 0.664
AUCI 0.43 2 0.805 6.48 2 0.039
Post hoc testing AUC I in high stressed subjects b     
  Z p r    
PAS 400 group vs. Placebo group −1.97 0.049 0.41    
PAS 400 group vs. PAS 200 group −2.37 0.018 0.51    
PAS 200 group vs. Placebo group −0.21 0.833     
serum cortisol c       
  F df, error df p F df, error df p
AUCG 0.44 2, 31 0.651 0.55 2, 30 0.585
AUCI 0.09 2, 31 0.911 4.87 2, 28 0.015
Post hoc testing AUC I in high stressed subjects d     
    p    
PAS 400 group vs. Placebo group    0.035    
PAS 400 group vs. PAS 200 group    0.033    
PAS 200 group vs. Placebo group    0.995    
ACTH e       
  F df, error df p F df, error df p
group difference 1.60 2, 30 0.218 2.43 2, 29 0.106
increase differences 0.31 2, 30 0.737 4.54 2, 29 0.019
Post hoc testing ACTH increase in high stressed subjects e     
  F df, error df p    
PAS 400 group vs. Placebo group 8.22 1, 19 0.010    
PAS 400 group vs. PAS 200 group 8.23 1, 20 0.009    
PAS 200 group vs. Placebo group 0.25 1, 19 0.627    
  1. PAS 200 group: 200 mg PA & 200 mg PS per day; PAS 400 group: 400 mg PA & 400 mg PS per day.
  2. Significant p-values are written in bold letters. Post hoc analyses are written in italic letters, ACTH = adrenocorticotropic hormone.
  3. a statistics based on Kruskal Wallis H Test.
  4. b statistics based on Mann–Whitney U test.
  5. c statistics based on univariate analysis of variance.
  6. d statistics based on Tukey post hoc testing.
  7. e statistics based on repeated measures analysis of variance.