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Table 3 Serum lipids (mg/dl) at the end of 4 weeks Benecol ® and at the end of placebo treatment

From: Efficacy of yogurt drink with added plant stanol esters (Benecol®, Colanta) in reducing total and LDL cholesterol in subjects with moderate hypercholesterolemia: a randomized placebo-controlled crossover trial NCT01461798

  Benecol Placebo Benecol® vs. placebo p
Mean (95% CI) Mean (95% CI) Mean (95% CI)
Total cholesterol (mg/dL) 205.5 (197.9 – 213.2) 221.1 (212.8 – 229.4) -15,6 (-24.2 to -6.9) 0.001
HDL cholesterol (mg/dL) 49.6 (45.8 - 53,4) 49.5 (45.1 – 53.9) 0.1 (-4.0 to 4.3) 0.95
LDL cholesterol measured (mg/dL) 108.7 (102.3 – 115.0) 120.7 (113.5 – 127.8) -12.0 (-16.5 to -7.5) <0.001
LDL cholesterol calculated (mg/dL) 125.8 (117.9 – 133.7) 142.2 (134.0 – 150.4) -16.4 (-23.4 to -9.3) <0.001
Non-HDL cholesterol (mg/dL) 155.9 (147.3 - 164.5) 171.6 (162.5 – 180.7) -15.7 (-23.0 to -8.3) <0.001
TG3 (mg/dL) 176.4 (137.2 – 215.7) 168.8 (138.7 – 198.9) 7.6 (-23.9 to 39.1) 0.63
  1. 3The distribution of TG was skew to the right.
  2. After logarithmic transformation, the geometric means were 146.2 in Benecol® and 149.4 in placebo (p = 0.76).