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Table 4 Percentage changes in serum lipids from first-period baseline to the end of 4 weeks Benecol and to the end of placebo treatment and differences in responses between treatments

From: Efficacy of yogurt drink with added plant stanol esters (Benecol®, Colanta) in reducing total and LDL cholesterol in subjects with moderate hypercholesterolemia: a randomized placebo-controlled crossover trial NCT01461798

  Benecol Placebo Benecol® vs. placebo p1
Mean (95% CI) Mean (95% CI) Mean (95% CI)
Total cholesterol -7.7 (-10.5 to -4.9) -0,5 (-4.0 to 3.1) -7.2 (-11.1 to -3.3) 0.001
HDL cholesterol -1,1 (-4.8 to 2.6) -0,1 (-6.9 to 6.8) -1.1 (-7.3 to 5.2) 0.735
LDL cholesterol measured -10,4 (-14.0 to -6.9) -0,1 (-5.1 to 4.9) -10.3 (-14.3 to -6.4) <0.001
LDL cholesterol calculated -11,5 (-16.6 to -6.4) 0,7 (-5.6 to 7.0) -12.2 (-17.3 to -7.2) <0.001
Non-HDL cholesterol -9,3 (-12.9 to -5.8) 0,2 (-4.5 to 5.0) -9.6 (-14.1 to -5.0) <0.001
TG3 18,2 (1.6 to 34.8) 18,2 (3.2 to 33.3) 0.0 (-18.9 to 18.9) 0.999
  1. 1Test.
  2. After logarithmic transformation the geometric means were 146.2 in Benecol® and 149.4 in placebo (p = 0.76).