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Table 2 Characteristics of randomized, controlled trials included in the meta-analysis

From: Effects of fish oil on serum lipid profile in dialysis patients: a systematic review and meta-analysis of randomized controlled trials

Reference Additional information Population Sex(M + F) Age HD + PD Duration Treatment group Control group
   F/C F/C F/C(SD or SE) F/C    
Diskin, 1990 [24] Unspecified 4/3 NA NA 4 + 0/3 + 0 24 w EPA (3 g/d) placebo
Donnelly, 1992 [25] 1DM 14/15 5 + 3/7 + 1 52 (14)/51 (12) 4 + 4/4 + 4 4 w fish oil (3.6 g/d) (12%DHA/18%EPA) olive oil
Ando, 1999 [26] HD:16DM/22, PD:0DM/16 19/19 17 + 2/16 + 3 54 (11)/51 (13) 11 + 8/11 + 8 3 m EPA (1.8 g/d) placebo
Khajehdehi, 2000 [27] DM 15% 15/15 8 + 7/7 + 8 32.7 (10.7)/31.1 (8.8) 15 + 0/15 + 0 2 m fish oil (1.5 g/d) corn oil (4.5 g/d), seasame oil (4.5 g/d), placebo
Schmitz, 2002 [28] Unspecified 12/12 5 + 7/6 + 6 52 (6)/54 (3) 12 + 0/12 + 0 3 m fish oil (4 g/d)(24%DHA/44%EPA) corn oil(4 g/d)
Saifullah, 2007 [14] Unspecified 15/8 11 + 4/7 + 1 58 (12)/57 (14) 15 + 0/8 + 0 12 w fish oil (DHA 170 mg/d × 2, EPA 340 mg/d × 2) placebo (soybean/corn oil mixture)
Svensson 2008 [29] Unspecified 35/38 NA NA 35 + 0/38 + 0 3 m omega-3 PUFA (1.7 g/d) (45%EPA/37.5%DHA) olive oil
Bowden, 2009 [20] Unspecified 44/43 25 + 19/20 + 23 59.3 (12.7)/60.8 (10.3) 44 + 0/43 + 0 6 m fish oil (6 g/d) (EPA 0.96 g/d, DHA 0.6 g/d) corn oil (6 g/d)
Poulia, 2011 [18] Unspecified 22/23 NA NA 22 + 0/23 + 0 4 w omega-3 (EPA 920 mg/d, DHA 760 mg/d) + VitE 8 mg/d VitE (14.2 mg/d)
Kooshki, 2011 [15] Unspecified 17/17 10 + 7/11 + 6 50 (18)/50 (17) 17 + 0/17 + 0 10 w omega-3 (2080 mg/d) (EPA 1240 mg/d, DHA 840 mg/d) placebo (medium chain triglycerides oil)
W.S. An, 2011 [30] Unspecified 7/7 4 + 3/3 + 4 51.6 (8.7)/52.6 (12.1) 0 + 7/0 + 7 12 w fish oil (3 g/d)EPA 460 mg/d × 3 + 380 mg DHA/d × 3 corn oil
Lok, 2012 [16] Unspecified 99/97 NA NA 99 + 0/97 + 0 6 m,12 m fish oil (4 g/d) (EPA 1600 mg/d, DHA 800 mg/d) olive oil (3 g/d)
Daud, 2012 [17] ALB < 3.9 g/dl 31/32 20 + 11/20 + 12 59 (13)/58 (12) 31 + 0/32 + 0 24 w protein + omega-3 (2.4 g) (EPA 1800 mg, DHA 600 mg), three times a week protein + olive oil, three times a week
  1. DM, diabetes; HD, hemodialysis; PD, peritoneal dialysis; NA, not available; F, fish oil group; C, control group.