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Table 4 FokI and BsmI polymorphisms and MS risk

From: Association of vitamin D receptor gene polymorphisms with metabolic syndrome: a case–control design of population-based cross-sectional study in North China

Genotype

MS n(%)

Control n(%)

P-value

OR

95% CI

BsmIa

     

BB(CC)

347(89.0)

328(82.0)

 

1

 

Bb(CT)

42(10.7)

69(17.3)

0.009

0.575

0.381-0.869

bb(TT)

1(0.3)

3(0.7)

0.318

0.315

0.033-3.044

Bb + bb

43

72

 

1

 

BB

347

328

0.006

1.771

1.179-2.661

B

736(94.4)

725(90.6)

 

1

 

b

44(5.6)

75(9.4)

0.005

0.578

0.393-0.850

FokIb

     

FF(AA)

75(19.2)

80(20.0)

 

1

 

Ff(AG)

184(47.1)

207(58.9)

0.779

0.948

0.653-1.376

ff(GG)

132(33.7)

112(28.1)

0.266

1.257

0.840-1.882

Ff + ff

316

319

 

1

 

FF

75

80

0.759

0.946

0.666-1.345

F

334(42.7)

367(46.0)

 

1

 

f

448(57.3)

431(54.0)

0.190

1.142

0.936-1.393

BBFFc

69

68

 

1

 

BBFf

164

174

0.761

0.929

0.624-1.382

BBff

114

85

0.211

1.322

0.854-2.046

BbFF

5

11

0.156

0.448

0.148-1.358

BbFf

19

32

0.111

0.585

0.303-1.131

Bbff

18

26

0.276

0.682

0.343-1.358

bbFF

0

1

1.000

0.000

0.000

bbFf

1

1

0.992

0.986

0.060-16.077

Bbff

0

1

1.000

0.000

0.000

  1. aP trend = 0.02; bP trend = 0.216; cP trend = 0.187;BB/FF normally show dominant homozygous genotype; Bb/Ff show heterozygous genotype; bb/ff show recessive homozygous genotype.