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Table 3 Effect of the triterpene on serum lipids and lipoproteins levels (mmol/L) in HFD-induced hyperlipidemia in rats

From: In vivo anti-hyperlipidemic activity of the triterpene from the stem bark of Protorhus longifolia (Benrh) Engl

Group

Total cholesterol

Triglyceride

VLDL-c

LDL-c

HDL-c

ND (after 21 days)

1.38 ± 0.12

0.68 ± 0.11

0.14 ± 0.04

0.11 ± 0.04

1.14 ± 0.90

(after 36 days)

1.83 ± 0.24

0.79 ± 0.06

0.26 ± 0.18

0.10 ± 0.02

1.86 ± 0.07

HFD (after 21 days)

15.72 ± 1.10

1.29 ± 0.54

0.28 ± 0.22

7.41 ± 0.56**

14.75 ± 0.19***

(after 36 days)

49.52 ± 4.83***

1.41 ± 0.35

0.28 ± 0.14

10.72 ± 0.94***

6.17 ± 0.16***

HFD/KE1 (100 mg/kg)

34.24 ± 1.50***

1.93 ± 0.15

0.39 ± 0.05

5.85 ± 0.81***

30.39 ± 0.92***

HFD/KE1 (200 mg/kg)

7.51 ± 0.97***

0.46 ± 0.05

0.09 ± 0.01

4.46 ± 0.82***

47.30 ± 0.9***

HFD/lovastatin (10 mg/kg)

38.66 ± 3.25*

0.77 ± 0.13

0.15 ± 0.03

12.97 ± 0.59

29.13 ± 0.68***

  1. All values are expressed as mean ± SEM, (n = 4); *p < 0.05, **p < 0.01 compared to the HFD 36 days; *p < 0.05, **p < 0.01, ***p < 0.001 compared to the ND 36 days.