Figure 1From: The rhythmic expression of clock genes attenuated in human plaque-derived vascular smooth muscle cellsThe morphologies and immunofluorescence analysis of VMSCs cultured from human plaque. (A) Cells starting to grow out radially from the explants within 7 to 12 days (red arrows). (B) Cells growing into cells and showing typical “hills and valleys” morphology in about 4 weeks. Larger “hills” form into nodules (red arrows); (C) α SMA expression in human plaque-derived VSMCs with a fusiform shape; cytoplasm (green), nucleus location (blue). (D) Uniform filamentous of α-SMA (red arrows) can be observed universally in human plaque-derived VSMCs with a big, flattened shape.Back to article page