Skip to main content

Advertisement

Table 4 ROC analysis represented as area under the curve (AUC), specificity and sensitivity for the measured PUFA in the PPA-intoxicated groups

From: Relative abundance of short chain and polyunsaturated fatty acids in propionic acid-induced autistic features in rat pups as potential markers in autism

  Area under the curve Best cutoff value Sensitivity % Specificity %
α-Linolenic 0.875 0.337 100.0% 87.5%
Eicosapentaenoic 0.883 0.405 87.5% 75.0%
Docosahexaenoic 0.938 0.595 100.0% 87.5%
Linoleic 1.000 0.386 100.0% 100.0%
γ-Linolenic 1.000 0.241 100.0% 100.0%
Arachidonic 0.938 0.338 87.5% 87.5%
Oleic 0.922 0.673 100.0% 87.5%
Total omega 3 0.609 1.690 75.0% 62.5%
Total omega 6 1.000 0.565 100.0% 100.0%
Omega6/omega 3 1.000 0.342 100.0% 100.0%
α-Linolenic/Linoleic 0.984 1.080 100.0% 87.5%
α-Linolenic/EPA 0.828 0.865 87.5% 87.5%
α-Linolenic/DHA 0.656 0.689 87.5% 62.5%
EPA/DHA 0.641 0.728 50.0% 100.0%
γ-Linolenic/ARA 1.000 0.817 100.0% 100.0%
ARA/EPA 0.625 0.896 87.5% 50.0%