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Table 4 ROC analysis represented as area under the curve (AUC), specificity and sensitivity for the measured PUFA in the PPA-intoxicated groups

From: Relative abundance of short chain and polyunsaturated fatty acids in propionic acid-induced autistic features in rat pups as potential markers in autism

 

Area under the curve

Best cutoff value

Sensitivity %

Specificity %

α-Linolenic

0.875

0.337

100.0%

87.5%

Eicosapentaenoic

0.883

0.405

87.5%

75.0%

Docosahexaenoic

0.938

0.595

100.0%

87.5%

Linoleic

1.000

0.386

100.0%

100.0%

γ-Linolenic

1.000

0.241

100.0%

100.0%

Arachidonic

0.938

0.338

87.5%

87.5%

Oleic

0.922

0.673

100.0%

87.5%

Total omega 3

0.609

1.690

75.0%

62.5%

Total omega 6

1.000

0.565

100.0%

100.0%

Omega6/omega 3

1.000

0.342

100.0%

100.0%

α-Linolenic/Linoleic

0.984

1.080

100.0%

87.5%

α-Linolenic/EPA

0.828

0.865

87.5%

87.5%

α-Linolenic/DHA

0.656

0.689

87.5%

62.5%

EPA/DHA

0.641

0.728

50.0%

100.0%

γ-Linolenic/ARA

1.000

0.817

100.0%

100.0%

ARA/EPA

0.625

0.896

87.5%

50.0%