Total | Men | Women | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
CAD | Control | p | CAD | Control | p | CAD | Control | p | ||||
n = 301 | n = 220 | n = 202 | n = 126 | n = 99 | n = 94 | |||||||
rs4086116 | Genotype | C/C | 237 | 176 | 0.356 | 158 | 97 | 0.464 | 79 | 79 | 0.559 | |
(SNP1) | C/T | 56 | 42 | 39 | 28 | 17 | 14 | |||||
T/T | 8 | 2 | 5 | 1 | 3 | 1 | ||||||
Dominant model | CC | 237 | 176 | 0.726 | 158 | 97 | 0.194 | 79 | 79 | 0.444 | ||
CT + TT | 64 | 44 | 44 | 29 | 20 | 15 | ||||||
Recessive model | TT | 8 | 2 | 0.151 | 5 | 1 | 0.269 | 3 | 1 | 0.338 | ||
CT + CC | 293 | 218 | 197 | 125 | 96 | 93 | ||||||
Allele | C | 530 | 394 | 0.449 | 355 | 222 | 0.932 | 175 | 172 | 0.312 | ||
T | 72 | 46 | 49 | 30 | 23 | 16 | ||||||
rs2475376 | Genotype | C/C | 104 | 76 | 0.834 | 60 | 51 | 0.122 | 44 | 25 | 0.033* | |
(SNP2) | C/T | 142 | 108 | 102 | 56 | 40 | 52 | |||||
T/T | 55 | 36 | 40 | 19 | 15 | 17 | ||||||
Dominant model | CC | 104 | 76 | 0.999 | 60 | 51 | 0.045* | 44 | 25 | 0.010* | ||
CT + TT | 197 | 144 | 142 | 75 | 55 | 69 | ||||||
Recessive model | TT | 55 | 36 | 0.571 | 40 | 19 | 0.279 | 15 | 17 | 0.584 | ||
CT + CC | 246 | 184 | 162 | 107 | 84 | 77 | ||||||
Allele | C | 350 | 260 | 0.758 | 222 | 158 | 0.051 | 128 | 102 | 0.038* | ||
T | 252 | 180 | 182 | 94 | 70 | 86 | ||||||
rs1057910 | Genotype | A/A | 237 | 178 | 0.282 | 156 | 96 | 0.76 | 81 | 82 | 0.174 | |
(SNP3) | A/C | 49 | 37 | 37 | 26 | 12 | 11 | |||||
C/C | 15 | 5 | 9 | 4 | 6 | 1 | ||||||
Dominant model | AA | 237 | 178 | 0.543 | 156 | 96 | 0.829 | 81 | 82 | 0.229 | ||
AC + CC | 64 | 42 | 46 | 30 | 18 | 12 | ||||||
Recessive model | CC | 15 | 5 | 0.112 | 9 | 4 | 0.563 | 6 | 1 | 0.063 | ||
AC + AA | 286 | 215 | 193 | 122 | 93 | 93 | ||||||
Allele | A | 523 | 393 | 0.233 | 349 | 218 | 0.965 | 174 | 175 | 0.082 | ||
C | 79 | 47 | 55 | 34 | 24 | 13 | ||||||
rs1934967 | Genotype | C/C | 209 | 152 | 0.126 | 144 | 79 | 0.203 | 65 | 73 | 0.161 | |
(SNP4) | C/T | 55 | 61 | 49 | 42 | 6 | 19 | |||||
T/T | 11 | 7 | 9 | 5 | 2 | 2 | ||||||
Dominant model | CC | 209 | 152 | 0.933 | 144 | 79 | 0.105 | 65 | 73 | 0.065 | ||
CT + TT | 92 | 68 | 58 | 47 | 34 | 21 | ||||||
Recessive model | TT | 11 | 7 | 0.77 | 9 | 5 | 0.832 | 2 | 2 | 0.958 | ||
CT + CC | 290 | 213 | 193 | 121 | 97 | 92 | ||||||
Allele | C | 499 | 365 | 0.978 | 337 | 200 | 0.19 | 162 | 165 | 0.105 | ||
T | 103 | 75 | 67 | 52 | 36 | 23 |