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Table 2 Genotype and allele distributions in patients with CAD and control subjects (Han population)

From: RETRACTED ARTICLE: A novel polymorphism of the GP78 gene is associated with coronary artery disease in Han population in China

  Total Men Women
  CAD n (%) Control n (%) P value CAD n (%) Control n (%) P value CAD n (%) Control n (%) P value
rs731119 (SNP1) Genotype   G/G 369 (60.8) 375 (64.1) 0.236 237 (61.2) 227 (63.9) 0.695 132 (60) 148 (64.3) 0.283
A/A 21 (3.5) 26 (4.4) 11 (2.8) 11 (3.1) 10 (4.5) 15 (6.5)
A/G 217 (35.7) 184 (31.5) 139 (35.9) 117 (33) 78 (35.5) 67 (29.1)
  Dominant model GG 369 (60.8) 375 (64.1) 0.238 237 (61.2) 227 (63.9) 0.447 132 (60) 148 (64.3) 0.342
AG + AA 238 (39.2) 210 (35.9) 150 (38.8) 128 (36.1) 88 (40) 82 (35.7)
Recessive model AA 21 (3.5) 26 (4.4) 0.382 11 (2.8) 11 (3.1) 0.837 10 (4.5) 15 (6.5) 0.36
AG + GG 572 (99.83) 455 (100) 376 (97.2) 344 (96.9) 210 (95.5) 215 (93.5)
Additive model AG 217 (35.7) 184 (31.5) 0.117 139 (35.9) 117 (33) 0.447 78 (35.5) 67 (29.1) 0.342
GG + AA 390 (64.3) 401 (68.5) 237 (61.2) 227 (63.9) 132 (60) 148 (64.3)
Allele   G 955 (78.7) 934 (79.8) 0.484 613 (79.2) 571 (80.4) 0.558 342 (77.7) 363 (78.9) 0.666
A 259 (21.3) 236 (20.2) 161 (20.8) 139 (19.6) 98 (22.3) 97 (21.1)
rs2617849 (SNP2) Genotype   T/T 222 (39.9) 181 (38.8) 0.046 132 (37.8) 102 (31.1) 0.159 90 (43.3) 79 (35.3) 0.234
C/C 74 (13.3) 87 (15.8) 49 (14) 56 (17.1) 25 (12) 31 (13.8)
C/T 261 (46.9) 284 (51.4) 168 (48.1) 170 (51.8) 93 (44.7) 114 (50.9)
  Dominant model TT 222 (39.9) 181 (38.8) 0.014* 132 (37.8) 102 (31.1) 0.066 90 (43.3) 79 (35.3) 0.89
CC + CT 335 (60.1) 371 (67.2) 217 (62.2) 226 (68.9) 118 (56.7) 145 (64.7)
Recessive model CC 74 (13.3) 87 (15.8) 0.242 49 (51.9) 56 (17.1) 0.276 25 (12) 31 (13.8) 0.574
TT + CT 483 (86.7) 465 (84.2) 300 (86) 272 (82.9) 183 (88) 193 (86.2)
Additive model CT 261 (46.9) 284 (51.4) 0.126 168 (48.1) 170 (51.8) 0.337 93 (44.7) 114 (50.9) 0.199
CC + TT 296 (53.1) 268 (48.6) 181 (51.9) 158 (48.2) 115 (55.3) 110 (49.1)
Allele   C 409 (37.7) 458 (41.5) 0.021* 266 (38.1) 282 (43) 0.068 143 (34.4) 176 (39.3) 0.135
T 705 (63.3) 646 (58.5) 432 (61.9) 374 (57) 273 (65.6) 272 (60.7)
rs2440472 (SNP3) Genotype   A/A 164 (27.2) 187 (32.7) 0.008* 110 (28.4) 123 (36.1) 0.007* 54 (25.2) 64 (27.7) 0.582
G/G 144 (23.9) 98 (17.1) 95 (24.5) 54 (15.8) 49 (22.9) 44 (19)
A/G 294 (48.8) 287 (50.2) 183 (47.2) 164 (48.1) 111 (51.9) 123 (53.2)
  Dominant model A/A 164 (27.2) 187 (32.7) 0.041* 110 (28.4) 123 (36.1) 0.026* 54 (25.2) 64 (27.7) 0.555
GG + AG 438 (72.8) 385 (67.3) 278 (71.6) 218 (63.9) 160 (74.8) 167 (72.3)
Recessive model GG 144 (23.9) 98 (17.1) 0.004* 95 (24.5) 54 (15.8) 0.004* 49 (22.9) 44 (19) 0.318
AA + AG 458 (76.1) 474 (82.9) 293 (75.5) 287 (84.2) 165 (77.1) 187 (81)
Additive model AG 294 (48.8) 287 (50.2) 0.647 183 (47.2) 164 (48.1) 0.802 111 (51.9) 123 (53.2) 0.771
AA + GG 308 (51.2) 285 (49.8) 205 (52.8) 177 (51.9) 103 (48.1) 108 (46.8)
Allele   A 622 (51.7) 661 (57.8) 0.003* 403 (51.9) 410 (60.1) 0.002* 219 (51.2) 251 (54.3) 0.345
    G 582 (48.3) 483 (42.2)   373 (48.1) 272 (39.9)   209 (48.8) 211 (45.7)  
  1. CAD, coronary artery disease.
  2. The P value of genotype was calculated by Fisher’s exact test. *P<0.05.