Total | Men | Women | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
CAD n (%) | Control n (%) | P value | CAD n (%) | Control n (%) | P value | CAD n (%) | Control n (%) | P value | ||||
rs731119 (SNP1) | Genotype | G/G | 269 (63) | 244 (64.4) | 0.811 | 202 (62.7) | 146 (63.8) | 0.873 | 67 (63.8) | 98 (65.3) | 0.968 | |
A/A | 18 (4.2) | 18 (4.7) | 12 (3.7) | 10 (4.4) | 6 (5.7) | 8 (5.3) | ||||||
A/G | 140 (32.8) | 117 (30.9) | 108 (33.5) | 73 (31.9) | 32 (30.5) | 44 (29.3) | ||||||
Dominant model | GG | 269 (63) | 244 (64.4) | 0.684 | 202 (62.7) | 146 (63.8) | 0.806 | 67 (63.8) | 98 (65.3) | 0.802 | ||
AG + AA | 158 (37) | 135 (35.6) | 120 (37.3) | 83 (36.2) | 38 (36.2) | 52 (34.7) | ||||||
Recessive model | AA | 18 (4.2) | 18 (4.7) | 0.714 | 12 (3.7) | 10 (4.4) | 0.705 | 6 (5.7) | 8 (5.3) | 0.895 | ||
AG + GG | 409 (95.8) | 361 (95.3) | 310 (96.3) | 219 (95.6) | 99 (94.3) | 142 (94.7) | ||||||
Additive model | AG | 140 (32.8) | 117 (30.9) | 0.56 | 108 (33.5) | 73 (31.9) | 0.682 | 32 (30.5) | 44 (29.3) | 0.844 | ||
GG + AA | 287 (67.2) | 262 (69.1) | 214 (66.5) | 156 (68.1) | 73 (69.5) | 106 (70.7) | ||||||
Allele | G | 678 (79.4) | 605 (79.8) | 0.833 | 512 (79.5) | 365 (79.7) | 0.938 | 166 (79) | 240 (80) | 0.793 | ||
A | 176 (20.6) | 153 (20.2) | 132 (20.5) | 93 (20.3) | 44 (21) | 60 (20) | ||||||
rs2617849 (SNP2) | Genotype | T/T | 152 (39.7) | 128 (35.4) | 0.576 | 120 (42.6) | 78 (36.1) | 0.346 | 32 (31.7) | 50 (34.2) | 0.869 | |
C/C | 57 (14.9) | 58 (16) | 36 (12.8) | 31 (14.4) | 21 (20.8) | 27 (18.5) | ||||||
C/T | 174 (45.4) | 176 (48.6) | 126 (44.7) | 107 (49.5) | 48 (47.5) | 69 (47.3) | ||||||
Dominant model | TT | 152 (39.7) | 128 (35.4) | 0.223 | 120 (42.6) | 78 (36.1) | 0.145 | 32 (31.7) | 50 (34.2) | 0.674 | ||
CC + CT | 231 (60.3) | 234 (64.6) | 162 (57.4) | 138 (63.9) | 69 (68.3) | 96 (65.8) | ||||||
Recessive model | CC | 57 (14.9) | 58 (16) | 0.667 | 36 (12.8) | 31 (14.4) | 0.607 | 21 (20.8) | 27 (18.5) | 0.653 | ||
TT + CT | 326 (85.1) | 304 (84) | 246 (87.2) | 185 (85.6) | 80 (79.2) | 119 (81.5) | ||||||
Additive model | CT | 174 (45.4) | 176 (48.6) | 0.384 | 126 (44.7) | 107 (49.5) | 0.282 | 48 (47.5) | 69 (47.3) | 0.967 | ||
CC + TT | 209 (54.6) | 186 (51.4) | 156 (55.3) | 109 (50.5) | 53 (52.5) | 77 (52.7) | ||||||
Allele | C | 288 (37.6) | 292 (40.3) | 0.279 | 198 (35.1) | 169 (39.1) | 0.193 | 90 (44.6) | 123 (42.1) | 0.592 | ||
T | 478 (62.4) | 432 (59.7) | 366 (64.9) | 263 (60.9) | 112 (55.4) | 169 (57.9) | ||||||
rs2440472 (SNP3) | Genotype | A/A | 85 (22.7) | 78 (20.7) | 0.269 | 57 (20.4) | 43 (19.1) | 0.316 | 28 (29.5) | 35 (23.2) | 0.513 | |
G/G | 120 (32.1) | 106 (28.2) | 94 (33.7) | 64 (28.4) | 26 (27.4) | 42 (27.8) | ||||||
A/G | 169 (45.2) | 192 (51.1) | 128 (45.9) | 118 (52.4) | 41 (43.2) | 74 (49) | ||||||
Dominant model | A/A | 85 (22.7) | 78 (20.7) | 0.51 | 57 (20.4) | 43 (19.1) | o.712 | 28 (29.5) | 35 (23.2) | 0.271 | ||
GG + AG | 289 (77.3) | 298 (79.3) | 222 (79.6) | 182 (80.9) | 67 (70.5) | 116 (76.8) | ||||||
Recessive model | GG | 120 (32.1) | 106 (28.2) | 0.245 | 94 (33.7) | 64 (28.4) | 0.207 | 26 (27.4) | 42 (27.8) | 0.939 | ||
AA + AG | 254 (67.9) | 270 (71.8) | 185 (66.3) | 161 (71.6) | 69 (72.6) | 109 (72.2) | ||||||
Additive model | AG | 169 (45.2) | 192 (51.1) | 0.107 | 128 (45.9) | 118 (52.4) | 0.143 | 41 (43.2) | 74 (49) | 0.371 | ||
AA + GG | 205 (54.8) | 184 (48.9) | 151 (54.1) | 107 (47.6) | 54 (56.8) | 77 (51) | ||||||
Allele | A | 339 (45.3) | 348 (46.3) | 0.71 | 242 (43.4) | 204 (45.3) | 0.533 | 97 (51.1) | 144 (47.7) | 0.467 | ||
G | 409 (54.7) | 404 (53.7) | 316 (56.6) | 246 (54.7) | 93 (48.9) | 158 (52.3) |