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Table 3 Genotype and allele distributions in patients with CAD and control subjects (Uygur population)

From: RETRACTED ARTICLE: A novel polymorphism of the GP78 gene is associated with coronary artery disease in Han population in China

  Total Men Women
  CAD n (%) Control n (%) P value CAD n (%) Control n (%) P value CAD n (%) Control n (%) P value
rs731119 (SNP1) Genotype   G/G 269 (63) 244 (64.4) 0.811 202 (62.7) 146 (63.8) 0.873 67 (63.8) 98 (65.3) 0.968
A/A 18 (4.2) 18 (4.7) 12 (3.7) 10 (4.4) 6 (5.7) 8 (5.3)
A/G 140 (32.8) 117 (30.9) 108 (33.5) 73 (31.9) 32 (30.5) 44 (29.3)
  Dominant model GG 269 (63) 244 (64.4) 0.684 202 (62.7) 146 (63.8) 0.806 67 (63.8) 98 (65.3) 0.802
AG + AA 158 (37) 135 (35.6) 120 (37.3) 83 (36.2) 38 (36.2) 52 (34.7)
Recessive model AA 18 (4.2) 18 (4.7) 0.714 12 (3.7) 10 (4.4) 0.705 6 (5.7) 8 (5.3) 0.895
AG + GG 409 (95.8) 361 (95.3) 310 (96.3) 219 (95.6) 99 (94.3) 142 (94.7)
Additive model AG 140 (32.8) 117 (30.9) 0.56 108 (33.5) 73 (31.9) 0.682 32 (30.5) 44 (29.3) 0.844
GG + AA 287 (67.2) 262 (69.1) 214 (66.5) 156 (68.1) 73 (69.5) 106 (70.7)
Allele   G 678 (79.4) 605 (79.8) 0.833 512 (79.5) 365 (79.7) 0.938 166 (79) 240 (80) 0.793
A 176 (20.6) 153 (20.2) 132 (20.5) 93 (20.3) 44 (21) 60 (20)
rs2617849 (SNP2) Genotype   T/T 152 (39.7) 128 (35.4) 0.576 120 (42.6) 78 (36.1) 0.346 32 (31.7) 50 (34.2) 0.869
C/C 57 (14.9) 58 (16) 36 (12.8) 31 (14.4) 21 (20.8) 27 (18.5)
C/T 174 (45.4) 176 (48.6) 126 (44.7) 107 (49.5) 48 (47.5) 69 (47.3)
  Dominant model TT 152 (39.7) 128 (35.4) 0.223 120 (42.6) 78 (36.1) 0.145 32 (31.7) 50 (34.2) 0.674
CC + CT 231 (60.3) 234 (64.6) 162 (57.4) 138 (63.9) 69 (68.3) 96 (65.8)
Recessive model CC 57 (14.9) 58 (16) 0.667 36 (12.8) 31 (14.4) 0.607 21 (20.8) 27 (18.5) 0.653
TT + CT 326 (85.1) 304 (84) 246 (87.2) 185 (85.6) 80 (79.2) 119 (81.5)
Additive model CT 174 (45.4) 176 (48.6) 0.384 126 (44.7) 107 (49.5) 0.282 48 (47.5) 69 (47.3) 0.967
CC + TT 209 (54.6) 186 (51.4) 156 (55.3) 109 (50.5) 53 (52.5) 77 (52.7)
Allele   C 288 (37.6) 292 (40.3) 0.279 198 (35.1) 169 (39.1) 0.193 90 (44.6) 123 (42.1) 0.592
T 478 (62.4) 432 (59.7) 366 (64.9) 263 (60.9) 112 (55.4) 169 (57.9)
rs2440472 (SNP3) Genotype   A/A 85 (22.7) 78 (20.7) 0.269 57 (20.4) 43 (19.1) 0.316 28 (29.5) 35 (23.2) 0.513
G/G 120 (32.1) 106 (28.2) 94 (33.7) 64 (28.4) 26 (27.4) 42 (27.8)
A/G 169 (45.2) 192 (51.1) 128 (45.9) 118 (52.4) 41 (43.2) 74 (49)
  Dominant model A/A 85 (22.7) 78 (20.7) 0.51 57 (20.4) 43 (19.1) o.712 28 (29.5) 35 (23.2) 0.271
GG + AG 289 (77.3) 298 (79.3) 222 (79.6) 182 (80.9) 67 (70.5) 116 (76.8)
Recessive model GG 120 (32.1) 106 (28.2) 0.245 94 (33.7) 64 (28.4) 0.207 26 (27.4) 42 (27.8) 0.939
AA + AG 254 (67.9) 270 (71.8) 185 (66.3) 161 (71.6) 69 (72.6) 109 (72.2)
Additive model AG 169 (45.2) 192 (51.1) 0.107 128 (45.9) 118 (52.4) 0.143 41 (43.2) 74 (49) 0.371
AA + GG 205 (54.8) 184 (48.9) 151 (54.1) 107 (47.6) 54 (56.8) 77 (51)
Allele   A 339 (45.3) 348 (46.3) 0.71 242 (43.4) 204 (45.3) 0.533 97 (51.1) 144 (47.7) 0.467
    G 409 (54.7) 404 (53.7)   316 (56.6) 246 (54.7)   93 (48.9) 158 (52.3)  
  1. CAD, coronary artery disease.
  2. The P value of genotype was calculated by Fisher’s exact test. *P<0.05.