Skip to main content

Table 2 Gene expression response according to genotypes of SNPs within SREBF1 gene

From: SREBF1 gene variations modulate insulin sensitivity in response to a fish oil supplementation

SNPs

Genotype

Fold change1

P-value2

rs12953299

A/A (n = 45)

1.04 ± 0.36

0.59

A/G (n = 98)

1.05 ± 0.27

 

G/G (n = 55)

1.00 ± 0.22

 

rs4925118

T/T + C/T (n = 66)

1.06 ± 0.26

0.47

C/C (n = 132)

1.02 ± 0.29

 

rs4925115

A/A (n = 32)

1.00 ± 0.25

0.25

A/G (n = 103)

1.07 ± 0.32

 

G/G (n = 63)

1.00 ± 0.23

 
  1. Means ± SD.
  2. 1The fold change represents post-supplementation relative gene expression levels compared to pre-supplementation relative gene expression levels.
  3. Fold change = 2-∆∆CT = 2-(post-supplementation ∆CT-pre-supplementation ∆CT).
  4. 2P- values were calculated with an ANOVA adjusted for age, sex and BMI.
  5. SNPs: single-nucleotide polymorphisms; SREBF1: sterol regulatory element binding transcription factor 1.
Back to article page

Lipids in Health and Disease

ISSN: 1476-511X