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Table 2 Relative risk for all-cause mortality, cardiovascular mortality, combined cardiovascular events, stroke, and coronary heart disease (with 95% confidence intervals) comparing the top versus bottom third of MUFA, MUFA:SFA ratio, olive oil, and oleic acid

From: Monounsaturated fatty acids, olive oil and health status: a systematic review and meta-analysis of cohort studies

Outcome No studies MUFA source Relative risk 95% CI p-value I2(%)a95% CI
All-cause mortality 17 All MUFA combined 0.89 0.83 to 0.96 0.001 64
42 to 78
  5 MUFA 1.00 0.93 to 1.08 0.93 23
  10 MUFA:SFA 0.90 0.82 to 1.00 0.04 59
  5 Olive oil 0.77 0.71 to 0.84 <0.00001 0
Cardiovascular mortality 14 All MUFA combined 0.88 0.80 to 0.96 0.004 50
15 to 71
  8 MUFA 0.96 0.89 to 1.04 0.36 7
  4 MUFA:SFA 0.91 0.83 to 0.99 0.04 0
  5 Olive oil 0.70 0.48 to 1.03 0.07 71
  1 Oleic acid 0.81 0.66 to 0.99 0.04 n.a.
Combined cardiovascular events 30 All MUFA combined 0.91 0.86 to 0.96 0.001 58
38 to 71
  20 MUFA 0.95 0.89 to 1.02 0.14 52
  6 MUFA:SFA 0.93 0.86 to 1.01 0.07 0
  7 Olive oil 0.72 0.57 to 0.91 0.007 75
  1 Oleic acid 0.87 0.76 to 1.00 0.04 n.a.
Stroke 11 All MUFA combined 0.83 0.71 to 0.97 0.02 70
46 to 84
  9 MUFA 0.85 0.72 to 1.01 0.07 65
  1 MUFA:SFA 1.18 0.91 to 1.53 0.21 n.a.
  2 Olive oil 0.60 0.47 to 0.77 <0.0001 0
Coronary heart disease 15 All MUFA combined 0.96 0.90 to 1.01 0.13 41
0 to 66
  9 MUFA 0.99 0.93 to 1.06 0.76 29
  4 MUFA:SFA 0.94 0.86 to 1.02 0.14 0
  4 Olive oil 0.80 0.57 to 1.14 0.22 77
  1 Oleic acid 0.87 0.76 to 1.00 0.04 n.a.
  1. aI2 inconsistency, percentage of variation across studies due to heterogeneity.
  2. MUFA monounsaturated fatty acids, n.a. not applicable, SFA saturated fatty acids.