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Table 4 Results of logistic regression analysis of the APOB polymorphisms and TG levels (Outcome variable TG; 0 = ≤1.7 mmol/L and 1= >1.7 mmol/L)

From: Genetic association of APOB polymorphisms with variation in serum lipid profile among the Kuwait population

 

Odds ratio (crude)

95% CIa

p-value

Odds ratio (adjusted)b

95% CIa

p-value

SP (rs11279109)

      

II

1.00

  

1.00

  

ID

0.49

0.29 – 0.82

0.007

0.53

0.31 – 0.92

0.023

DD

1.04

0.44 – 2.45

0.931

1.01

0.41 – 2.48

0.990

Xba1 (rs693)

      

XX

1.00

  

1.00

  

X+X

0.93

0.59 – 1.46

0.753

0.98

0.60 – 1.57

0.917

X+X+

0.76

0.31 – 1.88

0.558

0.82

0.32 – 2.11

0.680

Msp1 (rs1801701)

      

M+M+

1.00

  

1.00

  

M+M

0.62

0.29 – 1.33

0.220

0.72

0.32 – 1.61

0.424

MM

5.81

0.81 – 41.82

0.080

8.80

1.13 – 68.46

0.038

EcoR1 (rs1042031)

      

E+E+

1.00

  

1.00

  

E+E

0.95

0.53 – 1.70

0.867

0.93

0.50 – 1.71

0.810

EE

2.28

0.59 – 8.77

0.232

2.47

0.56 – 10.81

0.231

VNTR

      

MM

1.00

  

1.00

  

ML

0.65

0.32 – 1.29

0.217

0.66

0.32 – 1.37

0.264

LL

1.00

0.29 – 3.50

0.996

0.90

0.23 – 3.49

0.875

  1. The table summarizes the results for the signal peptide (SP) (rs11279109), variable number of tandem repeats (3’VNTR), Codons 2488-XbaI C(X) < T(X+) (rs693), 3611-MspI G(M) < A(M+) (rs1801701) and 4154-EcoRI G(E) < A(E+) (rs1042031).
  2. a95% CI = 95% confidence interval for odds ratio with significant p- value level at 0.05.
  3. bAdjusted for gender and age.