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Table 1 Comparison of characteristics between subjects with and without CKD (n = 3,268)

From: Polymorphisms of genes involved in lipid metabolism and risk of chronic kidney disease in Japanese - cross-sectional data from the J-MICC study

 

CKD (+)

CKD (-)

P

 

(n = 564)

(n = 2,704)

 

CKD stage 3 (eGFR < 60 ml/min/1.73m2)

561 (99.5%)

-

-

    Stage 4 (eGFR < 30)

0 (0%)

-

    Stage 5 (eGFR < 15)

3 (0.5%)

-

eGFR (ml/min/1.73m2)

53.7 ± 6.0

78.3 ± 12.5

< 0.001

Age (years)

60.4 ± 7.2

55.9 ± 8.7

< 0.001

Male

260 (46.1%)

1,327 (49.1%)

0.198

Body mass index

23.5 ± 3.1

23.4 ± 3.3

0.413

Systolic blood pressure (mm Hg)

130.1 ± 19.8

128.1 ± 19.4

0.029

Diastolic blood pressure (mm Hg)

78.8 ± 12.4

78.6 ± 11.9

0.746

Use of anti-hypertensive drugs

149 (26.4%)

486 (18.0%)

< 0.001

Fasting plasma glucose (mg/dL)

98.8 ± 22.1

100.0 ± 20.8

0.291

HbA1c (%)

5.22 ± 0.70

5.22 ± 0.66

0.942

Use of glucose-lowering drugs

31 (5.5%)

110 (4.1%)

0.129

Total cholesterol (mg/dL)

218.2 ± 34.0

211.1 ± 33.9

< 0.001

HDL cholesterol (mg/dL)

62.0 ± 15.9

63.3 ± 16.3

0.071

Triglyceride (mg/dL)*

106 (76.5-151)

104 (74-154)

0.992

Use of lipid-lowering drugs

70 (12.4%)

225 (8.3%)

0.002

Uric acid (mg/dL)

5.53 ± 1.47

5.10 ± 1.33

< 0.001

History of cardiovascular diseases

34 (6.0%)

80 (3.0%)

<0.001

History of cerebrovascular diseases

29 (5.1%)

52 (1.9%)

< 0.001

Current smokers

69 (12.2%)

484 (17.9%)

0.001

Current drinkers

295 (52.3%)

1,510 (55.8%)

0.138

  1. Values are expressed as means ± standard deviation, n (%), or median (interquartile range). CKD: chronic kidney disease. CKD was defined as estimated glomerular filtration rate <60 ml/min/1.73 m2.
  2. *Non-fasting.