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Table 1 Comparison of characteristics between subjects with and without CKD (n = 3,268)

From: Polymorphisms of genes involved in lipid metabolism and risk of chronic kidney disease in Japanese - cross-sectional data from the J-MICC study

  CKD (+) CKD (-) P
  (n = 564) (n = 2,704)  
CKD stage 3 (eGFR < 60 ml/min/1.73m2) 561 (99.5%) - -
    Stage 4 (eGFR < 30) 0 (0%) -
    Stage 5 (eGFR < 15) 3 (0.5%) -
eGFR (ml/min/1.73m2) 53.7 ± 6.0 78.3 ± 12.5 < 0.001
Age (years) 60.4 ± 7.2 55.9 ± 8.7 < 0.001
Male 260 (46.1%) 1,327 (49.1%) 0.198
Body mass index 23.5 ± 3.1 23.4 ± 3.3 0.413
Systolic blood pressure (mm Hg) 130.1 ± 19.8 128.1 ± 19.4 0.029
Diastolic blood pressure (mm Hg) 78.8 ± 12.4 78.6 ± 11.9 0.746
Use of anti-hypertensive drugs 149 (26.4%) 486 (18.0%) < 0.001
Fasting plasma glucose (mg/dL) 98.8 ± 22.1 100.0 ± 20.8 0.291
HbA1c (%) 5.22 ± 0.70 5.22 ± 0.66 0.942
Use of glucose-lowering drugs 31 (5.5%) 110 (4.1%) 0.129
Total cholesterol (mg/dL) 218.2 ± 34.0 211.1 ± 33.9 < 0.001
HDL cholesterol (mg/dL) 62.0 ± 15.9 63.3 ± 16.3 0.071
Triglyceride (mg/dL)* 106 (76.5-151) 104 (74-154) 0.992
Use of lipid-lowering drugs 70 (12.4%) 225 (8.3%) 0.002
Uric acid (mg/dL) 5.53 ± 1.47 5.10 ± 1.33 < 0.001
History of cardiovascular diseases 34 (6.0%) 80 (3.0%) <0.001
History of cerebrovascular diseases 29 (5.1%) 52 (1.9%) < 0.001
Current smokers 69 (12.2%) 484 (17.9%) 0.001
Current drinkers 295 (52.3%) 1,510 (55.8%) 0.138
  1. Values are expressed as means ± standard deviation, n (%), or median (interquartile range). CKD: chronic kidney disease. CKD was defined as estimated glomerular filtration rate <60 ml/min/1.73 m2.
  2. *Non-fasting.