Ampd2 deficiency and histological features in Ampd2m/mkidneys. A) Liver and kidney immunoblot analysis of Ampd2 protein in B6 Ampd2+/+ and Ampd2m/m mice. C) Proteinaceous tubular casts were observed in the kidneys of Ampd2m/m mice. D) Interstitial nephritis was observed in the kidneys of Ampd2m/m mice, but not in Ampd2+/+ mice (B). Bar = 100 μm.