Electron micropscopic evaluation of the glomeruli from Ampd2m/mmice. Glomeruli of Ampd2m/m mice showed diffuse effacement, sloughing, and fusing of podocyte foot processes (FP). Extensive blebbing, fusing, and surface pseudomembrane formation (PSM) was evident along the glomerular tuft endothelium of Ampd2m/m mice (white arrowheads). In addition to a minimal to moderate thickening of the basal lamina (GBM), there was a subtle increase in cellularity of the mesangial matrix (MM) and an increase in inflammatory cells, predominantly lymphocytes (LC) in Ampd2m/m mice. RBC = Red Blood Cell. Upper photomicrographs 4200×; lower photomicrographs 6000×; Bar = 2 μm.