Apolipoprotein C3 genetic polymorphisms are associated with lipids and coronary artery disease in a Chinese population

Table 1 General characteristics of cases and controls

	CAD	Controls	P
Number of subjects	600	600
Age (years), mean(SD)	57.3 ± 10.8	56.9 ± 10.1	0.51
Gender (Male/Female)	486/114	462/138	0.09
Smoking status (Ever/Never)	192/408	98/502	<0.001
Family history (Positive/Negative)	98/502	77/523	0.09
Hypertension (Positive/Negative)	305/295	280/320	0.15
Diabetes (Positive/Negative)	156/444	78/522	<0.001
Obesity (Positive/Negative)	176/424	85/515	<0.001
Hyperlipidemia (Positive/Negative)	188/412	92/508	<0.001
TG (mg/dL)	180.5 ± 92.3	151.7 ± 79.4	<0.001
TC (mg/dL)	202.1 ± 60.2	189.6 ± 47.9	<0.001
HDL-C (mg/dL)	37.4 ± 11.3	39.5 ± 12.4	0.002
LDL-C (mg/dL)	124.8 ± 49.8	116.7 ± 35.4	0.001
VLDL-C (mg/dL)	39.8 ± 23.7	32.7 ± 19.5	<0.001
ApoA1 (mg/dL)	127.3 ± 23.7	126.8 ± 22.9	0.71
ApoB (mg/dL)	90.6 ± 28.7	89.7 ± 24.5	0.56

Abbreviations: CAD coronary artery disease, TG triglyceride, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol VLDL-C very-low-density lipoprotein cholesterol, Apo apolipoprotein.

ISSN: 1476-511X