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Table 1 Morphometric comparison of SHR vs. SHR- Lx rats

From: Pharmacogenomic analysis of retinoic-acid induced dyslipidemia in congenic rat model

Trait

Standard diet

Standard diet + ATRA

SHR

SHR-Lx

SHR

SHR-Lx

 

(n = 7)

(n = 7)

(n = 7)

(n = 8)

Body weight, g

294 ± 6

275 ± 8

284 ± 7

265 ± 10

Liver, g/100 g b.wt.

3.73 ± 0.08

3.53 ± 0.05a

4.04 ± 0.09†

3.72 ± 0.03b

Heart, g/100 g b.wt.

0.40 ± 0.01

0.40 ± 0.02

0.41 ± 0.01

0.37 ± 0.01a

Kidney, g/100 g b.wt.

0.711 ± 0.003

0.65 ± 0.01c

0.71 ± 0.01

0.66 ± 0.01b

Adrenals, mg/100 g b.wt.

14.1 ± 0.3

15.7 ± 0.4b

14.4 ± 0.3

14.8 ± 0.4

EFP wt., g/100 g b.wt.

0.89 ± 0.03

0.84 ± 0.03

0.88 ± 0.03

0.83 ± 0.04

RFP wt., g/100 g b.wt.

1.05 ± 0.06

0.92 ± 0.05

1.02 ± 0.06

0.90 ± 0.06

  1. Morphometric profile of SHR vs. SHR-Lx rats. The significance levels are indicated as follows: a, b, c…p <0.05 and 0.01 and 0.001, respectively for differences between SHR and SHR-Lx under conditions of a single diet; †…p <0.01, respectively, for RA effect within individual strain. Values are shown as mean ± S.E.M.; b.wt….body weight; EFP…epididymal fat pad; RFP…retroperitoneal fat pad.