Skip to main content

Table 5 Multivariate logistic regression analyses for the interaction between atherogenic lipids and glycemic indices (GI) on the risk of arterial stiffness (baPWV ≥75 th percentile)

From: Additive effects of postchallenge hyperglycemia and low-density lipoprotein particles on the risk of arterial stiffness in healthy adults

 

AC

Glucose 30

Glucose 60

Glucose 90

Glucose 120

Glucose AUC

HbA1C

LDL-C ≥2/3 & GI ≥50%

2.63(1.59,4.35)‡

2.13(1.29,3.52)†

2.26(1.36,3.75)†

1.85(1.12,3.06)†

2.21(1.34,3.65)†

2.27(1.38,3.74)†

2.50(1.49,4.19)‡

LDL-C ≥2/3 & GI <50%

1.69(0.99,2.89)

1.28(0.74,2.21)

1.15(0.67,1.97)

1.55(0.90,2.65)

1.78(1.04,3.04)*

1.40(0.81,2.41)

1.89(1.13,3.16)*

LDL-C <2/3 & GI ≥50%

1.16(0.75,1.80)

0.68(0.43,1.08)

0.65(0.41,1.02)

0.71(0.45,1.12)

0.98(0.63,1.54)

0.84(0.53,1.32)

1.18(0.76,1.85)

LDL-C <2/3 & GI <50%

1

1

1

1

1

1

1

sdLDL-C ≥2/3 & GI ≥50%

2.05(1.26,3.33)†

1.70(1.02,2.82)*

1.63(1.00,2.66)*

1.47(0.91,2.40)

1.74(1.06,2.84)*

1.84(1.12,3.02)†

1.97(1.18,3.29)†

sdLDL-C ≥2/3 & GI <50%

1.20(0.68,2.13)

0.79(0.51,1.23)

1.34(0.76,2.35)

1.25(0.70,2.21)

1.38(0.79,2.41)

1.10(0.62,1.94)

1.50(0.89,2.54)

sdLDL-C <2/3 & GI ≥50%

1.12(0.72,1.73)

1.11(0.64,1.93)

0.87(0.56,1.36)

0.71(0.46,1.12)

0.99(0.64,1.54)

0.88(0.56,1.38)

1.21(0.78,1.88)

sdLDL-C <2/3 & GI <50%

1

1

1

1

1

1

1

  1. p-value: *<0.05, †<0.01, ‡<0.001.
  2. All models were after adjusting for age, male gender, BMI, hypertension, alcohol drinking and current smoker, in addition to glycemic indices and LDL-C (or sdLDL-C).
  3. Levels of LDL-C (130 mg/dL) and sdLDL-C (37 mg/dL) were set at cut point of ≥ upper tertile (2/3) (66.7th percentile) in the models.