Relation of plasma PCSK9 levels to lipoprotein subfractions in patients with stable coronary artery disease

Table 3 Independent associations of the PCSK9 levels with the lipid profile and lipoprotein subfractions in patients with CAD

Variables	Multivariable linear regression analysis
	Coefficients	P-value
TC (mg/dl)	0.215	0.000
TG (mg/dl)	0.042	0.494
Non-HDL-C (mg/dl)	0.202	0.001
Apo A-I (g/L)	0.137	0.025
Apo B (g/L)	0.245	0.000
LDL-C (mg/dl)	0.197	0.001
Large LDL-C (mg/dl)	0.033	0.590
Intermediate LDL-C (mg/dl)	0.152	0.013
Small LDL-C (mg/dl)	0.179	0.004
LDL score (% of sd-LDL)	0.121	0.043
Mean LDL size (Å)	-0.130	0.035
HDL-C (mg/dl)	0.056	0.334
Large HDL-C (mg/dl)	-0.050	0.380
Intermediate HDL-C (mg/dl)	0.069	0.276
Small HDL-C (mg/dl)	0.062	0.332

The multivariable linear regression analysis was adjusted for age, gender, BMI, hypertension, diabetes mellitus, current smoking and positive family history. The lipids and lipoprotein subfractions were the dependent variables.
TC: total cholesterol. TG: triglycerides. Non-HDL-C: non high-density lipoprotein cholesterol. ApoA-I: apolipoprotein A1. ApoB: apolipoprotein B. LDL-C: low-density lipoprotein-cholesterol. HDL-C: high-density lipoprotein cholesterol.

ISSN: 1476-511X