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Table 4 Comparisons of the clinical characteristics between male and female patients with CAD

From: Relation of plasma PCSK9 levels to lipoprotein subfractions in patients with stable coronary artery disease

Variables

Male (n = 199)

Female (n = 82)

P-value

Age (years)

56.79 ± 9.32

60.84 ± 9.56

0.001

BMI (kg/m2)

26.20 ± 3.14

25.35 ± 3.99

0.088

Hypertension [n (%)]

135 (67.8)

55 (67.1)

0.890

Diabetes [n (%)]

53 (26.6)

22 (26.8)

0.973

Dyslipidemia [n (%)]

135 (67.8)

62 (75.6)

0.251

Smoking [n (%)]

134 (67.3)

5 (6.1)

0.000

Family history of CHD [n (%)]

30 (15.1)

22 (26.8)

0.028

TC (mg/dl)

183.73 ± 40.76

205.99 ± 44.72

0.000

TG (mg/dl)

147.79 (106.19-208.85)

146.02 (98.23-207.30)

0.428

Non-HDL-C (mg/dl)

144.24 ± 40.11

156.33 ± 44.92

0.027

Apo A-I (g/L)

1.34 ± 0.21

1.52 ± 0.31

0.000

Apo B (g/L)

0.98 ± 0.27

1.07 ± 0.30

0.019

LDL-C (mg/dl)

110.07 ± 37.09

134.65 ± 40.78

0.001

 Large LDL-C (mg/dl)

26.80 ± 9.35

30.10 ± 10.05

0.009

 Intermediate LDL-C (mg/dl)

20.58 ± 9.01

21.38 ± 9.87

0.512

 Small LDL-C (mg/dl)

9.49 ± 10.57

8.79 ± 8.37

0.593

 LDL score (% of sd-LDL)

14.92 ± 14.23

13.42 ± 11.75

0.366

 Mean LDL size (Å)

265.74 ± 6.44

266.85 ± 5.15

0.168

HDL-C (mg/dl)

39.49 ± 11.68

49.67 ± 18.37

0.000

 Large HDL-C (mg/dl)

12.10 ± 5.40

17.49 ± 10.05

0.000

 Intermediate HDL-C (mg/dl)

19.76 ± 6.27

23.60 ± 8.91

0.001

 Small HDL-C (mg/dl)

7.99 ± 3.57

8.59 ± 3.28

0.214

 PCSK9 (ng/ml)

205.21 (174.32-247.02)

236.93 (193.10-283.64)

0.000

  1. BMI: body mass index. TC: total cholesterol. TG: triglycerides. Non-HDL-C: non high-density lipoprotein cholesterol. ApoA-I: apolipoprotein A1. ApoB: apolipoprotein B. LDL-C: low-density lipoprotein-cholesterol. HDL-C: high-density lipoprotein cholesterol.