Effects of Spirulina platensis supplementation on lipid profile in HIV–infected antiretroviral naïve patients in Yaounde - Cameroon: a randomized trial study

Table 4 Change in lipid profile during the six months of intervention and the follow up in each group

Variables	Ctrl/Spi	Period	Patients received local balance diet	Patients received spirulina combined with a local balance diet	*P-value*
Total cholesterol (mg/dL)	87/82	T0	194.8 ± 80.1	228.7 ± 96.8	0.17
	79/80	T6	216.8 ± 109.4	143.3 ± 45.4	<0.001
	66/79	T12	234.9 ± 101.8	141.4 ± 40.1	<0001
HDL cholesterol (mg/dL)	87/82	T0	53.6 ± 18.4	48.0 ± 21.1	0.71
	79/80	T6	49.9 ± 21.6	83.2 ± 39.7	<0. 001
	88/79	T12	57.3 ± 27.0	100.9 ± 28.7	<0.001
LDL cholesterol (mg/dL)	87/82	T0	120.12 ± 75.8	127.0 ± 92.2	0.60
	79/80	T6	138.3 ± 105.8	44.5 ± 33.0	<0.001
	66/79	T12	146.3 ± 97.8	29.3 ± 16.8	<0.001
Triglycerides (mg/dL)	87/82	T0	117.6 ± 76.8	206.9 ± 122.7	<0.0001
	79/80	T6	150.4 ± 97.5	139.8 ± 64.2	0.44
	66/79	T12	167.1 ± 124.8	123.5 ± 44.6	<0.01
CT/HDL (mg/dL)	87/82	T0	3.6 ± 4.3	4.7 ± 4.6	0.21
	79/80	T6	4.34 ± 5.1	1.7 ± 1.1	0.64
	66/79	T12	4.1 ± 3.0	1.4 ± 1.4	<0.0001
LDL/HDL (mg/dL)	87/82	T0	2.2 ± 4.1	2.6 ± 4.3	0.26
LDL/HDL (mg/dL)	79/80	T6	2.8 ± 4.89	0.53 ± 0.84	0.21
	66/79	T12	2.5 ± 3.6	0.3 ± 0.6	<0.0001

Mean values ± SD.
Ctrl: Control, Spi: Spirulina group; TC: HDL-C and LDL-C: HDL-C ratios were used to calculate the atherogenicity index. TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglycerides, P < 0.01: Significant difference between the group.

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