Protective effect of corn peptides against alcoholic liver injury in men with chronic alcohol consumption: a randomized double-blind placebo-controlled study

Table 4 Effects of treatments on GPx, SOD, MDA and TNF- α

Parameters	Placebo (n = 49)	Whey protein (n = 50)	Corn peptides (n = 47)	P value
GPx (U/mL)
Baseline	190.48 ± 3.88	184.01 ± 4.79	187.15 ± 4.29	0.571^A
∆9 weeks	4.86 ± 2.63^a	9.82 ± 2.60^a	24.97 ± 2.68^b	<0.001^B
SOD (U/mL)
Baseline	33.78 (28.59 - 36.64)	33.33 (24.88 - 38.55)	29.33 (25.53 - 34.19)	0.065^C
∆9 weeks	-0.16 ± 0.72^a	1.42 ± 0.70^a	7.83 ± 0.73^b	<0.001^B
MDA (nmol/mL)
Baseline	4.70 (4.36 - 5.30)	4.78 (4.24 - 5.30)	4.64 (4.39 - 5.25)	0.992^C
∆9 weeks	-0.08 ± 0.05^a	-0.20 ± 0.05^a	-0.41 ± 0.05^b	<0.001^B
TNF-α (pg/mL)
Baseline	95.85 (78.25 - 110.67)	83.24 (68.58 - 121.55)	104.10 (73.55 - 125.62)	0.228^C
∆9 weeks	-4.65 ± 2.17^a	-7.69 ± 2.15^a	-25.56 ± 2.22^b	<0.001^B

GPx, glutathione peroxidase; SOD, superoxide dismutase; MDA, malondialdehyde.
Values are means ± SE (baseline, normal distribution), medians with interquartile ranges in parentheses (baseline, skewed distribution) or least square means ± SE (change values). ^a,bMean values within a row with unlike superscript letters were significantly different (P < 0.05; ANCOVA followed by the least significant difference test). ^AANOVA F-test. ^BANCOVA with baseline values as a covariate. ^CKruskal-Wallis H test.

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