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Table 4 Age-adjusted mean levels * of fasting lipids, FPG and BMI by examination cycle in large sample

From: Secular trends in serum lipid levels of a Middle Eastern adult population; 10 years follow up in Tehran lipid and glucose study

 

Exam 1 (1999–2001)

Exam 2 (2002–2005)

Exam 3 (2005–2008)

Exam 4 (2008–2011)

p-value for trend

Male

     

  TC†

5.22 (5.21-5.23)

5.12 (5.10-5.13)

4.99 (4.95-5.00)

4.88 (4.87-4.90)

<0.001

  HDL-C†

0.943 (0.942-0.944)

0.982 (0.981-0.983)

1.016 (1.015-1.017)

1.052 (1.051-1.053)

<0.001

  TG†

2.08 (2.07-2.09)

2.01 (2.00-2.02)

1.96 (1.95-1.97)

1.90 (1.89-1.91)

<0.001

  Non-HDL-C†

4.28 (4.27-4.29)

4.13 (4.12-4.14)

3.97 (3.96-3.98)

3.82 (3.81-3.83)

<0.001

  TG/HDL-C

2.45 (2.44-2.47)

2.28 (2.27-2.30)

2.15 (2.14-2.16)

2.00 (1.99-2.01)

<0.001

  TC /HDL-C

5.81 (5.80-5.81)

5.48 (5.47-5.50)

5.17 (5.16-5.18)

4.85 (4.84-4.86)

<0.001

  FPG†

5.35 (5.32-5.37)

5.54 (5.51-5.57)

5.62 (5.59-5.64)

5.73 (5.71-5.75)

<0.001

  BMI (kg/m2)

25.88 (25.85-25.92)

26.36 (26.32-26.4)

26.87 (26.83-26.9)

27.37 (27.33-27.40)

<0.001

Female

     

  TC†

5.42 (5.40-5.44)

5.35 (5.33-5.37)

5.19 (5.17-5.21)

5.07 (5.05-5.09)

<0.001

  HDL-C†

1.1004 (1.1002-1.1007)

1.1486 (1.1484-1.1487)

1.1960 (1.195-1.197)

1.2450 (1.244-1.246)

<0.001

  TG†

1.86 (1.84-1.87)

1.84 (1.83-1.86)

1.76 (1.75-1.77)

1.71 (1.69-1.72)

<0.001

  Non-HDL-C†

4.32 (4.30-4.34)

4.2 (4.18-4.22)

4 (3.98-4.02)

3.83 (3.81-3.85)

<0.001

  TG/HDL-C

1.9 (1.88-1.91)

1.81 (1.80-1.82)

1.66 (1.64-1.70)

1.53 (1.52-1.54)

<0.001

  TC/HDL-C

5.19 (5.17-5.21)

4.93 (4.91-4.95)

4.6 (4.57-4.61)

4.28 (4.26-4.30)

<0.001

  FPG†

5.47 (5.44-5.49)

5.63 (5.60-5.66))

5.63 (5.61-5.66)

5.78 (5.75-5.81)

0.37

  BMI (kg/m2)

27.73 (27.63-27.78)

26.64 (28.57-28.7)

29.24 (29.18-29.3)

29.94 (29.88-30.0)

<0.001

  1. Abbreviations: BMI body mass index, Exam examination cycle, FPG fasting plasma glucose, HDL-C high-density lipoprotein cholesterol, non HDL-C non-high-density lipoprotein cholesterol, TC total cholesterol, TG triglycerides.
  2. *Values are age adjusted means (95% confidence intervals) from generalized estimating equations to account for correlated observations. Adjusted for age, propensity score and examination cycle.
  3. †mmol/L.