| Exam 1 (1999–2001) | Exam 2 (2002–2005) | Exam 3 (2005–2008) | Exam 4 (2008–2011) | p-value for trend |
---|---|---|---|---|---|
Male | Â | Â | Â | Â | Â |
  TC†| 5.22 (5.21-5.23) | 5.12 (5.10-5.13) | 4.99 (4.95-5.00) | 4.88 (4.87-4.90) | <0.001 |
  HDL-C†| 0.943 (0.942-0.944) | 0.982 (0.981-0.983) | 1.016 (1.015-1.017) | 1.052 (1.051-1.053) | <0.001 |
  TG†| 2.08 (2.07-2.09) | 2.01 (2.00-2.02) | 1.96 (1.95-1.97) | 1.90 (1.89-1.91) | <0.001 |
  Non-HDL-C†| 4.28 (4.27-4.29) | 4.13 (4.12-4.14) | 3.97 (3.96-3.98) | 3.82 (3.81-3.83) | <0.001 |
  TG/HDL-C | 2.45 (2.44-2.47) | 2.28 (2.27-2.30) | 2.15 (2.14-2.16) | 2.00 (1.99-2.01) | <0.001 |
  TC /HDL-C | 5.81 (5.80-5.81) | 5.48 (5.47-5.50) | 5.17 (5.16-5.18) | 4.85 (4.84-4.86) | <0.001 |
  FPG†| 5.35 (5.32-5.37) | 5.54 (5.51-5.57) | 5.62 (5.59-5.64) | 5.73 (5.71-5.75) | <0.001 |
  BMI (kg/m2) | 25.88 (25.85-25.92) | 26.36 (26.32-26.4) | 26.87 (26.83-26.9) | 27.37 (27.33-27.40) | <0.001 |
Female | Â | Â | Â | Â | Â |
  TC†| 5.42 (5.40-5.44) | 5.35 (5.33-5.37) | 5.19 (5.17-5.21) | 5.07 (5.05-5.09) | <0.001 |
  HDL-C†| 1.1004 (1.1002-1.1007) | 1.1486 (1.1484-1.1487) | 1.1960 (1.195-1.197) | 1.2450 (1.244-1.246) | <0.001 |
  TG†| 1.86 (1.84-1.87) | 1.84 (1.83-1.86) | 1.76 (1.75-1.77) | 1.71 (1.69-1.72) | <0.001 |
  Non-HDL-C†| 4.32 (4.30-4.34) | 4.2 (4.18-4.22) | 4 (3.98-4.02) | 3.83 (3.81-3.85) | <0.001 |
  TG/HDL-C | 1.9 (1.88-1.91) | 1.81 (1.80-1.82) | 1.66 (1.64-1.70) | 1.53 (1.52-1.54) | <0.001 |
  TC/HDL-C | 5.19 (5.17-5.21) | 4.93 (4.91-4.95) | 4.6 (4.57-4.61) | 4.28 (4.26-4.30) | <0.001 |
  FPG†| 5.47 (5.44-5.49) | 5.63 (5.60-5.66)) | 5.63 (5.61-5.66) | 5.78 (5.75-5.81) | 0.37 |
  BMI (kg/m2) | 27.73 (27.63-27.78) | 26.64 (28.57-28.7) | 29.24 (29.18-29.3) | 29.94 (29.88-30.0) | <0.001 |