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Table 6 Proportions of participants in Lipid-related categories * by examination cycle in large sample

From: Secular trends in serum lipid levels of a Middle Eastern adult population; 10 years follow up in Tehran lipid and glucose study

 

Male

    

Female

    
 

Exam 1 (1999–2001)

Exam 2 (2002–2005)

Exam 3 (2005–2008)

Exam 4 (2008–2011)

p-value for trend

Exam 1 (1999–2001)

Exam 2 (2002–2005)

Exam 3 (2005–2008)

Exam 4 (2008–2011)

p-value for trend

Age adjusted †

          

  High cholesterol

18.3

14.9

11.7

9.2

<0.001

24.8

22.1

17.3

14.2

<0.001

  Low HDL-C

72.2

66.4

60.8

54.6

<0.001

46.2

39.4

32.9

27.1

<0.001

  High Triglycerides

33.1

30.1

27.8

25.4

<0.001

26.0

25.2

22.6

21.0

<0.001

  High Non-HDL-C

20.3

15.8

11.9

9.0

<0.001

23.1

19.2

13.8

10.3

<0.001

  High TG/HDL-C

40.2

44.3

38.4

25.4

<0.001

28.3

25.9

22.3

19.6

<0.001

  High TC /HDL-C

37.6

42.5

30.3

14.7

<0.001

26.8

21.1

14.9

10.7

<0.001

  Lipid drug (%)

1.4

2.9

5.0

8.8

<0.001

3.6

5.8

7.8

11.2

<0.001

Multivariate adjusted ‡

          

  High cholesterol

18.1

15.2

11.8

9.4

<0.001

24.5

22.5

17.2

14.1

<0.001

  Low HDL-C

71.0

67.8

61.2

53.6

<0.001

45.4

40.6

33.1

26.5

<0.001

  High Triglycerides

33.7

29.1

27.2

26.5

<0.001

26.6

24.4

21.3

21.9

<0.001

  High Non-HDL-C

19.9

16.2

12.1

9.0

<0.001

22.9

19.7

13.6

10.2

<0.001

  High TG/HDL-C

32.2

39.4

34.1

29.7

<0.001

28.0

26.8

21.8

19.5

<0.001

  High TC /HDL-C

41.3

34.4

26.0

19.1

<0.001

26.7

21.8

14.8

10.6

<0.001

  Lipid drug (%)

1.5

2.9

4.8

9.0

<0.001

3.7

6.1

7.6

11.4

<0.001

  1. Abbreviations: Exam examination cycle, HDL-C high-density lipoprotein cholesterol, non HDL-C non-high-density lipoprotein cholesterol, TC total cholesterol, TG triglycerides.
  2. Definitions: High cholesterol ≥6.19 mmol/L; Low HDL-C <1.036 mmol/L; High Triglycerides ≥2.26 mmol/L; High Non-HDL-C ≥5.15 mmol/L; High TG/HDL-C ≥2.18; High TC /HDL-C ≥5.97.
  3. *Values are age and multivariate adjusted percentage from pooled logistic regressions including examination cycle to account for correlated observations.
  4. †Adjusted for age, propensity score, and examination cycle.
  5. ‡Adjusted for age, propensity score, examination cycle, BMI, current smoking, hypertension, Diabetes (except for FPG) and total cholesterol (in analyses of HDL-C and TGs), using covariates from the examination in question.
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Lipids in Health and Disease

ISSN: 1476-511X