| Exam 1 (1999–2001) | Exam 2 (2002–2005) | Exam 3 (2005–2008) | Exam 4 (2008–2011) | p-value for trend |
---|---|---|---|---|---|
Male | Â | Â | Â | Â | Â |
  TC†| 5.13 (5.12-5.15) | 5.08 (5.06-5.1) | 5.00 (4.99-5.2) | 4.93 (4.91-4.95) | <0.001 |
  HDL-C†| 0.940 (0.930-0.950) | 0.970 (0.900-0.980) | 1.012 (1.008-1.016) | 1.058 (1.053-1.060) | <0.001 |
  TG†| 1.97 (1.95-1.99) | 1.95 (1.93-1.98) | 1.91 (1.88-1.94) | 1.89 (1.86-1.91) | <0.001 |
  Non-HDL-C†| 4.19 (4.17-4.21) | 4.11 (4.09-4.13) | 3.99 (3.97-4.00) | 3.86 (3.84-3.88) | <0.001 |
  TG/HDL-C†| 2.32 (2.29-2.35) | 2.22 (2.19-2.26) | 2.10 (2.07-2.13) | 1.96 (1.93-1.99) | <0.001 |
  TC/HDL-C | 5.72 (5.69-5.75) | 5.48 (5.45-5.51) | 5.19 (5.16-5.22) | 4.86 (4.83-4.90) | <0.001 |
  FPG†| 5.14 (5.12-5.16) | 5.30 (5.28-5.32) | 5.45 (5.44-5.47) | 5.62 (5.60-5.63) | 0.048 |
  BMI, (kg/m2) | 25.91 (25.84-25.99) | 26.3 (26.22-26.37) | 26.78 (26.7-26.86) | 27.45 (27.35-27.53) | <0.001 |
Female | Â | Â | Â | Â | Â |
  TC†| 5.18 (5.15-5.20) | 5.15 (5.13-5.18) | 5.09 (5.06-5.11) | 5.05 (5.03-5.07) | <0.001 |
  HDL-C†| 1.094 (1.092-1.096) | 1.144 (1.141-1.146) | 1.202 (1.199-1.204) | 1.256 (1.254-1.259) | <0.001 |
  TG†| 1.62 (1.60-1.64) | 1.63 (1.61-1.65) | 1.59 (1.57-1.61) | 1.60 (1.58-1.62) | <0.001 |
  Non-HDL-C†| 4.08 (4.06-4.11) | 4.01 (3.98-4.03) | 3.88 (3.86-3.91) | 3.80 (3.77-3.82) | <0.001 |
  TG/HDL-C†| 1.63 (1.61-1.65) | 1.6 (1.57-1.60) | 1.47 (1.45-1.49) | 1.42 (1.40-1.44) | <0.001 |
  TC/HDL-C | 4.96 (4.94-5.00) | 4.75 (4.72-4.77) | 4.46 (4.43-4.48) | 4.21 (4.19-4.23) | <0.001 |
  FPG†| 5.10 (5.08-5.12) | 5.24 (5.21-5.26) | 5.34 (5.31-5.36) | 5.50 (5.48-5.50) | 0.05 |
  BMI, (kg/m2) | 27.46 (27.38-27.54) | 28.15 (28.07-28.23) | 28.73 (28.65-28.81) | 29.58 (29.5-29.67) | <0.001 |