| Male |  |  |  |  | Female |  |  |  |  |
---|---|---|---|---|---|---|---|---|---|---|
 | Exam 1 (1999–2001) | Exam 2 (2002–2005) | Exam 3 (2005–2008) | Exam 4 (2008–2011) | p-value for trend | Exam 1 (1999–2001) | Exam 2 (2002–2005) | Exam 3 (2005–2008) | Exam 4 (2008–2011) | p-value for trend |
Age adjusted †|  |  |  |  |  |  |  |  |  |  |
  High cholesterol | 15.6 | 13.2 | 11.2 | 9.4 | <0.001 | 18.0 | 16.4 | 14.6 | 13.4 | <0.001 |
  Low HDL-C | 72.4 | 66.7 | 60.5 | 53.8 | <0.001 | 46.8 | 39.2 | 32.1 | 25.7 | <0.001 |
  High Triglycerides | 31.2 | 27.9 | 27.3 | 24.6 | <0.001 | 18.3 | 17.1 | 18.1 | 16.8 | <0.001 |
  High Non-HDL-C | 17.3 | 13.9 | 11.1 | 8.8 | <0.001 | 16.1 | 13.1 | 10.4 | 8.4 | <0.001 |
  High TG/HDL-C | 42.6 | 38.0 | 33.7 | 29.4 | <0.001 | 21.4 | 19.5 | 17.5 | 15.9 | <0.001 |
  High TC/HDL-C | 40.4 | 32.2 | 24.9 | 18.8 | <0.001 | 21.4 | 16.1 | 11.7 | 8.6 | <0.001 |
Multivariate adjusted ‡ |  |  |  |  |  |  |  |  |  |  |
  High cholesterol | 15.5 | 13.4 | 11.4 | 9.7 | <0.001 | 17.7 | 16.6 | 14.7 | 13.5 | <0.001 |
  Low HDL-C | 71.7 | 67.0 | 60.9 | 53.0 | <0.001 | 42.2 | 40.0 | 32.1 | 25.4 | <0.001 |
  High Triglycerides | 31.1 | 28.0 | 27.6 | 24.7 | <0.001 | 18.1 | 17.1 | 17.9 | 16.6 | <0.001 |
  High Non-HDL-C | 17.0 | 14.2 | 11.3 | 9.0 | <0.001 | 15.9 | 13.4 | 10.4 | 8.5 | <0.001 |
  High TG/HDL-C | 42.1 | 38.7 | 34.8 | 29.4 | <0.001 | 21.2 | 19.9 | 17.2 | 15.9 | <0.001 |
  High TC/HDL-C | 39.8 | 33.0 | 25.4 | 18.6 | <0.001 | 21.2 | 16.5 | 11.7 | 8.4 | <0.001 |