Apolipoprotein E polymorphism is associated with lower extremity deep venous thrombosis: color-flow Doppler ultrasound evaluation

Table 3 Stratification analysis of APOE genotype frequency in LEDVT patients

Variable	Cases	E2/E2		E2/E3		E2/E4		E3/E3		E3/E4		E4/E4
Variable	Cases	n (%)	P	n (%)	P	n (%)	P	n (%)	P	n (%)	P	n (%)	P
Smoking status	300	3(1.0)		1(0.3)		1(0.3)		185(61.7)		105(35.0)		5(1.7)
Ever	122	1(0.8)	0.86	0(0)	0.90	0(0)	0.90	71(58.2)	0.74	48(39.3)	0.57	2(1.6)	0.98
Never	178	2(1.1)	0.90	1(0.6)	0.71	1(0.6)	0.71	114(64.0)	0.80	57(32.0)	0.64	3(1.7)	0.99
Presence of varicose veins	300	3(1.0)		1(0.3)		1(0.3)		185(61.7)		105(35.0)		5(1.7)
YES	72	1(1.4)	0.78	0(0)	0.84	0(0)	0.84	45(62.5)	0.95	25(34.7)	0.98	1(1.4)	0.87
NO	228	2(0.9)	0.89	1(0.4)	0.85	1(0.4)	0.85	140(61.4)	0.98	80(35.1)	0.99	4(1.8)	0.94
Type 2 diabetes mellitus	300	3(1.0)		1(0.3)		1(0.3)		185(61.7)		105(35.0)		5(1.7)
YES	25	1(4.0)	0.24	0(0)	0.41	0(0)	0.41	16(64.0)	0.91	7(28.0)	0.61	1(4.0)	0.43
NO	275	2(0.7)	0.73	1(0.4)	0.95	1(0.4)	0.95	169(61.5)	0.98	98(35.6)	0.91	4(1.4)	0.84
Any hormone administration before	300	3(1.0)		1(0.3)		1(0.3)		185(61.7)		105(35.0)		5(1.7)
YES	30	1(3.3)	0.30	0(0)	0.47	0(0)	0.47	18(60.0)	0.93	9(30.0)	0.70	2(6.7)	0.11
NO	270	2(0.7)	0.74	1(0.4)	0.94	1(0.4)	0.94	167(61.9)	0.98	96(35.5)	0.92	3(1.1)	0.58
Family history of DVT	300	3(1.0)		1(0.3)		1(0.3)		185(61.7)		105(35.0)		5(1.7)
Positive	58	1(1.7)	0.64	0(0)	0.74	0(0)	0.74	22(37.9)	0.07	34(58.6)	0.04	1(1.7)	0.98
Negative	242	2(0.8)	0.84	1(0.4)	0.88	1(0.4)	0.88	163(67.4)	0.52	71(29.3)	0.32	4(1.7)	0.99

ISSN: 1476-511X