| CD | CD + ATV2 | HD | HD + ATV1 | HD + ATV2 | HD + ATV3 |
---|
| | (0.56 mg/day) | | (0.2 mg/day) | (0.56 mg/day) | (1.42 mg/day) |
---|
TC | | | | | | |
Without CoQ10 | 2.71 ± 0.86 | 2.77 ± 0.33 | 12.43 ± 2.84a | 7.80 ± 1.73b | 8.71 ± 0.62b | 7.38 ± 1.15b |
With CoQ10 | 2.30 ± 0.75 | 1.87 ± 0.34a,1 | 6.42 ± 0.86a,1 | 2.42 ± 0.47b,1 | 2.25 ± 0.46b,1 | 3.30 ± 0.75b,1 |
TAG | | | | | | |
Without CoQ10 | 5.58 ± 0.88 | 7.53 ± 0.45a | 10.66 ± 0.33a | 9.73 ± 1.95 | 9.70 ± 1.50 | 6.31 ± 2.23b |
With CoQ10 | 4.30 ± 0.551 | 6.24 ± 1.16a,1 | 10.70 ± 0.32a | 3.73 ± 0.60b,1 | 2.81 ± 0.11b, 1 | 6.47 ± 0.20b |
- CD, control diet; CD + ATV2, CD + atorvastatin 0.56 mg/day; HD, hypercholesterolemic diet; HD + ATV1, 0.2 mg/day; HD + ATV2 0.56 mg/day; HD + ATV3 1.42 mg/day, Coenzyme Q10, 0.57 mg/day; Data are expressed as mean ± S.E.M.; n = 8. One-way analysis of variance (ANOVA) (groups CD, CD + ATV2, HD, HD + ATV1, HD + ATV2, HD + ATV3) accompanied by the Student-Newman-Keuls test and differences between the groups were determined by the Student's t test (Without CoQ10 vs With CoQ10) (p < 0.05). aStatistically different from either CD or CD + CoQ10 (p < 0.05); bstatistically different from either HD or HD + CoQ10 (p < 0.05); 1statistically different from the same group without CoQ10.