Table 2 The association analysis between SNPs in PPAR-α/γ and dyslipidemia
From: PPAR α and PPAR γ Polymorphisms as risk factors for Dyslipidemia in a Chinese han population
SNP | Model | Genotype | Non- dyslipidemia(N = 628) | Dyslipidemia(N = 192) | OR (95%CI) | P |
|---|---|---|---|---|---|---|
rs1800206 | ||||||
Codominant | LL | 524 | 98 | 1.0 | <0.001 | |
LV | 99 | 92 | 5.75 (3.91-8.46) | |||
VV | 5 | 2 | 2.38 (0.43-13.31) | |||
Log additive | - | - | - | 4.74 (3.29-6.84) | <0.001 | |
rs4253778 | ||||||
Codominant | CC | 469 | 146 | 1.0 | 0.670 | |
CG | 133 | 41 | 0.95 (0.63-1.43) | |||
GG | 26 | 5 | 0.65 (0.24-1.78) | |||
Log additive | - | - | - | 0.89 (0.64-1.23) | 0.470 | |
rs3856806 | ||||||
Codominant | CC | 343 | 75 | 1.0 | 0.005 | |
CT | 237 | 89 | 1.58 (1.09-2.27) | |||
TT | 48 | 28 | 2.23 (1.28-3.90) | |||
Log additive | - | - | - | 1.53 (1.19-1.97) | <0.001 | |
rs1805192 | ||||||
Codominant | ProPro | 380 | 79 | 1.0 | <0.001 | |
ProAla | 206 | 82 | 1.77 (1.22-2.56) | |||
AlaAla | 42 | 31 | 2.96 (1.70-5.14) | |||
Log additive | - | - | - | 1.76 (1.36-2.27) | <0.001 |