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Figure 1 | Lipids in Health and Disease

Figure 1

From: The effects of obesity, diabetes and metabolic syndrome on the hydrolytic enzymes of the endocannabinoid system in animal and human adipocytes

Figure 1

Endocannabinoid degradation enzyme assay validation. FAAH activity was detected in the total particulate and not cytosolic fraction of adipocyte homogenates of Zucker rats (A, n = 48), and was significantly inhibited by URB597 (1 μM, C, n = 48). MGL activity was detected in the cytosolic and not total particulate fraction of adipocyte homogenates (B, n = 33), and was significantly inhibited by MAFP (1 μM, D, n = 66). Data are given as means with error bars representing S.E.M and were analysed by a Mann–Whitney test (*** P < 0.001, *** P < 0.001).

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