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Table 2 Association of haplotypes in APOA5 and ZNF259 gene regions with log[TG]:HDL-C ratio

From: Effects of apolipoprotein A5 haplotypes on the ratio of triglyceride to high-density lipoprotein cholesterol and the risk for metabolic syndrome in Koreans

Subject Hap 1 & 2 11/12/22 [n] 11/12/22 [mean (sd)] Effect (95% CI)* P*
All ht1, ht2 1,398/838/115 0.0448 (0.0145)/0.0471 (0.0155)/0.0509 (0.0165) 0.00222 (0.00130 - 0.00315) 2.68E-06
  ht1, ht3 1,398/340/17 0.0448 (0.0145)/0.0491 (0.0173)/0.0587 (0.0154) 0.00460 (0.00313 - 0.00607) 1.05E-09
  ht2, ht3 115/123/17 0.0509 (0.0165)/0.0537 (0.0180)/0.0587 (0.0154) 0.00289 (-0.000221 - 0.00599) 0.0686
Men ht1, ht2 482/325/42 0.0508 (0.0155)/0.0528 (0.0156)/0.0609 (0.0159) 0.00328 (0.00154 - 0.00502) 2.25E-04
  ht1, ht3 482/124/5 0.0508 (0.0155)/0.0567 (0.0176)/0.0590 (0.0125) 0.00606 (0.00324 - 0.00888) 2.83E-05
  ht2, ht3 42/54/5 0.0609 (0.0159)/0.0605 (0.0194)/0.0590 (0.0125) 0.00122 (-0.00486 - 0.00731) 0.690
Women ht1, ht2 916/513/73 0.0417 (0.0128)/0.0435 (0.0143)/0.0452 (0.0140) 0.00157 (0.000507 - 0.00264) 3.84E-03
  ht1, ht3 916/216/12 0.0417 (0.0128)/0.0447 (0.0156)/0.0585 (0.0170) 0.00391 (0.00223 - 0.00558) 5.20E-06
  ht2, ht3 73/69/12 0.0452 (0.0140)/0.0484 (0.0150)/0.0585 (0.0170) 0.00473 (0.00130 - 0.00816) 7.16E-03
  1. *The effect (beta), 95% confidence interval (CI), and p-value for Hap 2 versus Hap 1 were estimated by linear regression, after adjusting for age, sex (in all subjects), physical activity (three categories), daily food intake (three categories), clinical history, and medications for hypertension, dyslipidemia, and/or diabetes.