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Table 6 Relative risks (RR) and 95% confidence intervals (95% CI) for the presence of a risk factor for cardiovascular disease in the entire cohort

From: Risk stratification of patients with familial hypercholesterolemia in a multi-ethnic cohort

 

Univariate

Multivariate (n = 409)

 

RR

95% CI

P value

RR

95% CI

P value

Diabetes (present vs. absent)

3.2

1.9-5.6

<0.001

3.6

2.0-6.5

<0.001

Male sex

2.9

2.0-4.3

<0.001

2.4

1.6-3.7

<0.001

Lp (a) (high vs. low)*

1.6

1.0-2.6

0.033

1.8

1.1-2.9

0.014

HDL-C (mmol L-1)

0.2

0.1-0.4

<0.001

0.4

0.2-0.7

0.004

Family history pre-mature CVD

1.5

1.1-2.3

0.026

1.8

1.2-2.7

0.005

LDL-C (mmol L-1)

0.8

0.6-0.9

0.002

0.8

0.7-0.9

0.001

Smoking (ever vs. never)

2.1

1.4-3.0

<0.001

-

-

-

  1. *:Lp (a) analysis carried out on the 276 FH patients with Lp (a) data available.