Figure 4
From: L-arginine conjugates of bile acids-a possible treatment for non-alcoholic fatty liver disease
Effect of CDCArg on hepatic enzyme levels in the serum, liver weight and liver histology. Mice were fed (ad libitum) for 5 weeks with LFD, HFD, HFD + CA, HFD + CDCArg and HFD + Arg. (A-C) Serum SGPT, SGOT or Alkaline Phosphatase levels. (D) Liver weight. (E) Representative liver histological sections stained with H&E: (magnification 400X). Arrows indicate hepatocytes steatosis and Arrow heads indicate hepatocytes damage (necrosis or apoptosis). Values are expressed as mean ± SEM (n = 8-9 animals per group). Means with different letters are statistically different. Means with *are statistically higher compare to all other groups, p < 0.05.