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Table 3 Genotyping and allele distributions in control subjects and patients with CAD in the Han population

From: Association of Egr 3 genetic polymorphisms and coronary artery disease in the Uygur and Han of China

  Total Men Women
Variants CAD patients Control subjects P value CAD patients Control subjects P value CAD patients Control subjects P value
rs1996147          
Genotyping          
AA 45(11.0%) 49(14.0%)   35(11.7%) 28(15.6%)   10(9.2%) 21(12.2%)  
AG 199(48.7%) 156(44.4%)   150(50.0%) 77(43.1%)   49(45.0%) 79(45.9%)  
GG 165(40.3%) 146(41.6%) 0.346 115(38.3%) 74(41.3%) 0.252 50(45.8%) 72(41.9%) 0.664
Dominant model          
GG 165(40.3%) 146(41.6%)   115(38.3%) 74(41.3%)   50(45.8%) 72(41.9%)  
AA + AG 244(59.7%) 205(58.4%) 0.726 185(61.7%) 105(58.7%) 0.515 59(54.2%) 100(58.1%) 0.509
Recessive model          
AA 45(11.0%) 49(14.0%)   35(11.7%) 28(15.6%)   10(9.2%) 21(12.2%)  
GG + AG 364(89.0%) 302(86.0%) 0.217 265(88.3%) 151(84.4%) 0.213 99(90.8%) 151(87.8%) 0.429
Additive model          
AG 199(48.7%) 156(44.4%)   150(50.0%) 77(43.1%)   49(45.0%) 79(45.9%)  
AA + GG 210(51.3%) 195(55.6%) 0.246 150(50.0%) 102(56.9%) 0.139 60(55.0%) 93(54.1%) 0.873
Allele          
A 289(35.3%) 254(36.2%)   220(36.7%) 133(37.2%)   69(31.7%) 121(35.2%)  
G 529(64.7%) 448(63.8%) 0.730 380(63.3%) 225(62.8%) 0.881 149(68.3%) 223(64.8%) 0.390
rs1008949          
Genotyping          
CC 112(27.4%) 99(28.2%)   85(28.3%) 55(30.7%)   30(27.5%) 44(25.6%)  
CT 204(49.9%) 173(49.3%)   149(49.7%) 84(46.9%)   55(50.5%) 89(51.7%)  
TT 93(22.7%) 79(22.5%) 0.969 69(23.0%) 40(22.4%) 0.817 24(22.0%) 39(22.7%) 1.000
Dominant model          
CC 112(27.4%) 99(28.2%)   85(28.3%) 55(30.7%)   30(27.5%) 44(25.6%)  
TT + CT 297(72.6%) 252(71.8%) 0.801 218(72.7%) 124(69.3%) 0.532 79(72.5%) 128(74.4%) 0.719
Recessive model          
TT 93(22.7%) 79(22.5%)   69(23.0%) 40(22.4%)   24(22.0%) 39(22.7%)  
CC + CT 316(77.3%) 272(77.5%) 0.939 234(77.0%) 139(77.6%) 0.914 85(78.0%) 133(77.3%) 0.995
Additive model          
CT 204(49.9%) 173(49.3%)   149(46.7%) 84(46.9%)   55(50.5%) 89(51.7%)  
CC + TT 205(50.1%) 178(50.7%) 0.871 154(51.3%) 95(53.1%) 0.633 54(49.5%) 83(48.3%) 0.982
Allele          
C 428(52.3%) 371(52.8%)   319(53.2%) 194(54.2%)   115(52.8%) 177(51.5%)  
T 390(47.7%) 331(47.2%) 0.838 287(47.8%) 164(45.8%) 0.641 103(47.2%) 167(48.5%) 0.993
  1. CAD, coronary artery disease; SNP, single-nucleotide polymorphism.